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Weight Loss Strategies in the Elderly: A Clinical Conundrum

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Date 2017 Dec 22
PMID 29265771
Citations 16
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Abstract

The age-related concomitant loss of skeletal muscle and accumulation of excess adipose tissue have been commonly referred to as sarcopenic obesity. While weight loss may help mitigate the metabolic abnormalities linked to obesity, low fitness levels and muscle atrophy complicate the effectiveness of lifestyle interventions. Because of low levels of compliance, suboptimal economic efficiency, and low functional capacity, there has been no consensus on optimal therapy. This includes the use of high-protein diets that do not ensure muscle preservation during weight loss in this segment of the population. The primary objectives of this review are to discuss the relevance of sarcopenic obesity, examine the feasibility of weight loss in the elderly, and highlight new approaches to the problem.

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References
1.
Tanner R, Brunker L, Agergaard J, Barrows K, Briggs R, Kwon O . Age-related differences in lean mass, protein synthesis and skeletal muscle markers of proteolysis after bed rest and exercise rehabilitation. J Physiol. 2015; 593(18):4259-73. PMC: 4594296. DOI: 10.1113/JP270699. View

2.
Milne A, Potter J, Avenell A . Protein and energy supplementation in elderly people at risk from malnutrition. Cochrane Database Syst Rev. 2002; (3):CD003288. DOI: 10.1002/14651858.CD003288. View

3.
Coker R, Hays N, Williams R, Xu L, Wolfe R, Evans W . Bed rest worsens impairments in fat and glucose metabolism in older, overweight adults. J Gerontol A Biol Sci Med Sci. 2013; 69(3):363-70. PMC: 3976140. DOI: 10.1093/gerona/glt100. View

4.
Holst M, Beermann T, Mortensen M, Skadhauge L, Kohler M, Lindorff-Larsen K . Optimizing protein and energy intake in hospitals by improving individualized meal serving, hosting and the eating environment. Nutrition. 2017; 34:14-20. DOI: 10.1016/j.nut.2016.05.011. View

5.
Bauer J, Biolo G, Cederholm T, Cesari M, Cruz-Jentoft A, Morley J . Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE Study Group. J Am Med Dir Assoc. 2013; 14(8):542-59. DOI: 10.1016/j.jamda.2013.05.021. View