The Basic Science and Molecular Mechanisms of Lung Injury and Acute Respiratory Distress Syndrome

Overview

Journal Int Anesthesiol Clin

Specialty Anesthesiology

Date 2017 Dec 12

PMID 29227309

Citations 11

Authors

Paola Aranda-Valderrama

Ata Murat Kaynar

Affiliations

Soon will be listed here.

Citing Articles

Circulating Nucleosomes and Histones in the Development of Lung Injury and Sepsis.

Dutta S, Dutta S, Somanath P, Narayanan S, Wang X, Zhang D Curr Issues Mol Biol. 2025; 47(2).

PMID: 39996854 PMC: 11854804. DOI: 10.3390/cimb47020133.

Anion gap predicting 90-Day mortality and guiding furosemide use in ARDS.

Li Y, Luo W, Wang Q, Chen Y, Bai F, Zeng Q Sci Rep. 2025; 15(1):4954.

PMID: 39930113 PMC: 11811161. DOI: 10.1038/s41598-025-89163-1.

[Proposal for the use of anakinra in acute respiratory distress secondary to COVID-19].

Munoz-Jimenez A, Rubio-Romero E, Marenco de la Fuente J Reumatol Clin. 2024; 17(6):309-312.

PMID: 38620280 PMC: 7183956. DOI: 10.1016/j.reuma.2020.04.009.

Synergistic Pulmonoprotective Effect of Natural Prolyl Oligopeptidase Inhibitors in In Vitro and In Vivo Models of Acute Respiratory Distress Syndrome.

Zerikiotis S, Efentakis P, Dapola D, Agapaki A, Seiradakis G, Kostomitsopoulos N Int J Mol Sci. 2023; 24(18).

PMID: 37762537 PMC: 10531912. DOI: 10.3390/ijms241814235.

Progress in non-viral localized delivery of siRNA therapeutics for pulmonary diseases.

Gao J, Xia Z, Vohidova D, Joseph J, Luo J, Joshi N Acta Pharm Sin B. 2023; 13(4):1400-1428.

PMID: 37139423 PMC: 10150162. DOI: 10.1016/j.apsb.2022.07.010.

References

Keshari R, Silasi-Mansat R, Zhu H, Popescu N, Peer G, Chaaban H . Acute lung injury and fibrosis in a baboon model of Escherichia coli sepsis. Am J Respir Cell Mol Biol. 2013; 50(2):439-50. PMC: 3930952. DOI: 10.1165/rcmb.2013-0219OC. View

Deng X, Jin K, Li Y, Gu W, Liu M, Zhou L . Platelet-Derived Growth Factor and Transforming Growth Factor β1 Regulate ARDS-Associated Lung Fibrosis Through Distinct Signaling Pathways. Cell Physiol Biochem. 2015; 36(3):937-46. DOI: 10.1159/000430268. View

Bachofen M, Weibel E . Alterations of the gas exchange apparatus in adult respiratory insufficiency associated with septicemia. Am Rev Respir Dis. 1977; 116(4):589-615. DOI: 10.1164/arrd.1977.116.4.589. View

Brown S, Grissom C, Rondina M, Hoidal J, Scholand M, Wolff R . Polymorphisms in key pulmonary inflammatory pathways and the development of acute respiratory distress syndrome. Exp Lung Res. 2014; 41(3):155-62. PMC: 4406221. DOI: 10.3109/01902148.2014.983281. View

Peters A, Van Stein D, Vlaar A . Antibody-mediated transfusion-related acute lung injury; from discovery to prevention. Br J Haematol. 2015; 170(5):597-614. DOI: 10.1111/bjh.13459. View

Briassoulis G, Papassotiriou I, Mavrikiou M, Lazaropoulou C, Margeli A . Longitudinal course and clinical significance of TGF-beta1, sL- and sE-Selectins and sICAM-1 levels during severe acute stress in children. Clin Biochem. 2007; 40(5-6):299-304. DOI: 10.1016/j.clinbiochem.2006.11.015. View

Silversides J, Ferguson N . Clinical review: Acute respiratory distress syndrome - clinical ventilator management and adjunct therapy. Crit Care. 2013; 17(2):225. PMC: 3672489. DOI: 10.1186/cc11867. View

Porta C, Rimoldi M, Raes G, Brys L, Ghezzi P, Di Liberto D . Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB. Proc Natl Acad Sci U S A. 2009; 106(35):14978-83. PMC: 2736429. DOI: 10.1073/pnas.0809784106. View

Moazed F, Calfee C . Environmental risk factors for acute respiratory distress syndrome. Clin Chest Med. 2014; 35(4):625-37. PMC: 4255333. DOI: 10.1016/j.ccm.2014.08.003. View

10.

Bhargava M, Runyon M, Smirnov D, Lei J, Groppoli T, Mariash C . Triiodo-L-thyronine rapidly stimulates alveolar fluid clearance in normal and hyperoxia-injured lungs. Am J Respir Crit Care Med. 2008; 178(5):506-12. PMC: 2542429. DOI: 10.1164/rccm.200709-1429OC. View

11.

Halter J, Steinberg J, Gatto L, DiRocco J, Pavone L, Schiller H . Effect of positive end-expiratory pressure and tidal volume on lung injury induced by alveolar instability. Crit Care. 2007; 11(1):R20. PMC: 2151879. DOI: 10.1186/cc5695. View

12.

Azevedo Z, Moore D, Lima F, Cardoso C, Bougleux R, Matos G . Tumor necrosis factor (TNF) and lymphotoxin-alpha (LTA) single nucleotide polymorphisms: importance in ARDS in septic pediatric critically ill patients. Hum Immunol. 2012; 73(6):661-7. DOI: 10.1016/j.humimm.2012.03.007. View

13.

Narasaraju T, Yang E, Perumal Samy R, Ng H, Poh W, Liew A . Excessive neutrophils and neutrophil extracellular traps contribute to acute lung injury of influenza pneumonitis. Am J Pathol. 2011; 179(1):199-210. PMC: 3123873. DOI: 10.1016/j.ajpath.2011.03.013. View

14.

Andre P, Prele C, Vierkotten S, Carnesecchi S, Donati Y, Chambers R . BARD1 mediates TGF-β signaling in pulmonary fibrosis. Respir Res. 2015; 16:118. PMC: 4587901. DOI: 10.1186/s12931-015-0278-3. View

15.

Overgaard C, Schlingmann B, Dorsainvil White S, Ward C, Fan X, Swarnakar S . The relative balance of GM-CSF and TGF-β1 regulates lung epithelial barrier function. Am J Physiol Lung Cell Mol Physiol. 2015; 308(12):L1212-23. PMC: 4499033. DOI: 10.1152/ajplung.00042.2014. View

16.

Greinacher A, Wesche J, Hammer E, Furll B, Volker U, Reil A . Characterization of the human neutrophil alloantigen-3a. Nat Med. 2009; 16(1):45-8. DOI: 10.1038/nm.2070. View

17.

Hsu A, Barrett C, DeBusk G, Ellson C, Gautam S, Talmor D . Kinetics and Role of Plasma Matrix Metalloproteinase-9 Expression in Acute Lung Injury and the Acute Respiratory Distress Syndrome. Shock. 2015; 44(2):128-36. PMC: 4830084. DOI: 10.1097/SHK.0000000000000386. View

18.

Ware L, Matthay M . Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med. 2001; 163(6):1376-83. DOI: 10.1164/ajrccm.163.6.2004035. View

19.

Herwig M, Tsokos M, Hermanns M, Kirkpatrick C, Muller A . Vascular endothelial cadherin expression in lung specimens of patients with sepsis-induced acute respiratory distress syndrome and endothelial cell cultures. Pathobiology. 2013; 80(5):245-51. DOI: 10.1159/000347062. View

20.

Bjornsdottir H, Welin A, Michaelsson E, Osla V, Berg S, Christenson K . Neutrophil NET formation is regulated from the inside by myeloperoxidase-processed reactive oxygen species. Free Radic Biol Med. 2015; 89:1024-35. DOI: 10.1016/j.freeradbiomed.2015.10.398. View