Bioactive Steroids and Saponins of the Genus Trillium

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2017 Dec 6

PMID 29206216

Citations 15

Authors

Shafiq Ur Rahman

Muhammad Ismail

Muhammad Khurram

Irfan Ullah

Fazle Rabbi

Marcello Iriti

Affiliations

Soon will be listed here.

Abstract

The species of the genus (Melanthiaceae alt. Trilliaceae) include perennial herbs with characteristic rhizomes mainly distributed in Asia and North America. Steroids and saponins are the main classes of phytochemicals present in these plants. This review summarizes and discusses the current knowledge on their chemistry, as well as the in vitro and in vivo studies carried out on the extracts, fractions and isolated pure compounds from the different species belonging to this genus, focusing on core biological properties, i.e., cytotoxic, antifungal and anti-inflammatory activities.

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