Steroidal Glycosides from the Underground Parts of Trillium Erectum and Their Cytotoxic Activity

Overview

Journal Phytochemistry

Publisher Elsevier

Specialties Biochemistry
Biology
Chemistry

Date 2008 Sep 30

PMID 18822438

Citations 14

Authors

Akihito Yokosuka

Yoshihiro Mimaki

Affiliations

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Abstract

Six steroidal glycosides, along with 14 known compounds, were isolated from the underground parts of Trillium erectum L. (Liliaceae). The structures of 1-6 were determined on the basis of extensive spectroscopic analysis, including two-dimensional (2D) NMR data, and a few chemical transformations. The isolated compounds were evaluated for their cytotoxic activity against HL-60 human promyelocytic leukemia cells.

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