What is the Relationship Between Physical Activity and Cardiovascular Risk Factors in Stroke Survivors Post Completion of Rehabilitation? Protocol for a Longitudinal Study

Overview

Journal BMJ Open

Specialty General Medicine

Date 2017 Nov 18

PMID 29146661

Citations 2

Authors

Natalie A Fini

Julie Bernhardt

Anne E Holland

Affiliations

Soon will be listed here.

Abstract

Introduction: Physical activity (PA) can modify cardiovascular and other health risks in people with stroke, but we know little about long-term PA in this group. This study aims to describe PA levels and investigate relationships between PA, cardiovascular risk factors, mobility and participant characteristics (eg, age, mood and fatigue) in the 2 years following rehabilitation discharge after first stroke.

Methods And Analysis: This is a longitudinal observational study with follow-up at 6, 12 and 24 months after rehabilitation discharge. Inclusion criteria are broad; excluding only those with previous stroke, palliative diagnosis, living more than 2 hours from the centre or admitted less than 5 days.The primary outcome of interest is duration of moderate to vigorous PA (min/day) measured by the Sensewear MF Armband (SWAB). Secondary outcomes include other PA measures measured with the SWAB; cardiovascular risk factors (eg, systolic blood pressure, fasting lipid profile and smoking status), mobility (10 m walk test), the Hospital Anxiety and Depression Scale and the Fatigue Severity Scale. All outcomes, except blood tests, are gathered at each time point.The target sample size is 77. We will explore associations between PA levels, cardiovascular risk factors, mobility and participant characteristics at baseline compared with 6, 12 and 24 months using random-effects regression modelling.The long-term PA of stroke survivors is largely unknown. We hope to identify factors that influence PA and cardiovascular risk in this population, which may help health professionals target the stroke survivors most at risk and implement appropriate treatment, preventative strategies and education.

Ethics And Dissemination: Approval was granted from Alfred Hospital and La Trobe University Research Ethics Committees. The study results will be disseminated in a number of ways including journal publication and international conference presentations.

Trial Registration Number: ACTRN12613000196741.

Citing Articles

Types of physical activity performed pre and post stroke.

Fini N, Bernhardt J, Holland A Braz J Phys Ther. 2022; 26(3):100412.

PMID: 35487096 PMC: 9062242. DOI: 10.1016/j.bjpt.2022.100412.

How Many Hours of Device Wear Time Are Required to Accurately Measure Physical Activity Post Stroke?.

Fini N, Holland A, Bernhardt J, Burge A Int J Environ Res Public Health. 2022; 19(3).

PMID: 35162217 PMC: 8834432. DOI: 10.3390/ijerph19031191.

References

Moore S, Hallsworth K, Bluck L, Ford G, Rochester L, Trenell M . Measuring energy expenditure after stroke: validation of a portable device. Stroke. 2012; 43(6):1660-2. DOI: 10.1161/STROKEAHA.111.646257. View

Hackett M, Yapa C, Parag V, Anderson C . Frequency of depression after stroke: a systematic review of observational studies. Stroke. 2005; 36(6):1330-40. DOI: 10.1161/01.STR.0000165928.19135.35. View

Bernhardt J, Dewey H, Thrift A, Donnan G . Inactive and alone: physical activity within the first 14 days of acute stroke unit care. Stroke. 2004; 35(4):1005-9. DOI: 10.1161/01.STR.0000120727.40792.40. View

Moore S, Hallsworth K, Plotz T, Ford G, Rochester L, Trenell M . Physical activity, sedentary behaviour and metabolic control following stroke: a cross-sectional and longitudinal study. PLoS One. 2013; 8(1):e55263. PMC: 3558428. DOI: 10.1371/journal.pone.0055263. View

Cereda E, Pezzoli G, Barichella M . Role of an electronic armband in motor function monitoring in patients with Parkinson's disease. Nutrition. 2009; 26(2):240-2. DOI: 10.1016/j.nut.2009.06.003. View

Hardie K, Hankey G, Jamrozik K, Broadhurst R, Anderson C . Ten-year survival after first-ever stroke in the perth community stroke study. Stroke. 2003; 34(8):1842-6. DOI: 10.1161/01.STR.0000082382.42061.EE. View

Mudge S, Stott N . Timed walking tests correlate with daily step activity in persons with stroke. Arch Phys Med Rehabil. 2009; 90(2):296-301. DOI: 10.1016/j.apmr.2008.07.025. View

Chiti G, Pantoni L . Use of Montreal Cognitive Assessment in patients with stroke. Stroke. 2014; 45(10):3135-40. DOI: 10.1161/STROKEAHA.114.004590. View

Michael K, Goldberg A, Treuth M, Beans J, Normandt P, Macko R . Progressive adaptive physical activity in stroke improves balance, gait, and fitness: preliminary results. Top Stroke Rehabil. 2009; 16(2):133-9. PMC: 2934904. DOI: 10.1310/tsr1602-133. View

10.

English C, Healy G, Coates A, Lewis L, Olds T, Bernhardt J . Sitting and Activity Time in People With Stroke. Phys Ther. 2015; 96(2):193-201. DOI: 10.2522/ptj.20140522. View

11.

Camillo C, Pitta F, Possani H, Barbosa M, Marques D, Cavalheri V . Heart rate variability and disease characteristics in patients with COPD. Lung. 2008; 186(6):393-401. DOI: 10.1007/s00408-008-9105-7. View

12.

Samitz G, Egger M, Zwahlen M . Domains of physical activity and all-cause mortality: systematic review and dose-response meta-analysis of cohort studies. Int J Epidemiol. 2011; 40(5):1382-400. DOI: 10.1093/ije/dyr112. View

13.

Haskell W, Lee I, Pate R, Powell K, Blair S, Franklin B . Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc. 2007; 39(8):1423-34. DOI: 10.1249/mss.0b013e3180616b27. View

14.

Kunkel D, Fitton C, Burnett M, Ashburn A . Physical inactivity post-stroke: a 3-year longitudinal study. Disabil Rehabil. 2014; 37(4):304-10. DOI: 10.3109/09638288.2014.918190. View

15.

Tseng B, Billinger S, Gajewski B, Kluding P . Exertion fatigue and chronic fatigue are two distinct constructs in people post-stroke. Stroke. 2010; 41(12):2908-12. PMC: 3711242. DOI: 10.1161/STROKEAHA.110.596064. View

16.

Smith Jr S, Benjamin E, Bonow R, Braun L, Creager M, Franklin B . AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients with Coronary and other Atherosclerotic Vascular Disease: 2011 update: a guideline from the American Heart Association and American College of Cardiology Foundation. Circulation. 2011; 124(22):2458-73. DOI: 10.1161/CIR.0b013e318235eb4d. View

17.

Duncan F, Wu S, Mead G . Frequency and natural history of fatigue after stroke: a systematic review of longitudinal studies. J Psychosom Res. 2012; 73(1):18-27. DOI: 10.1016/j.jpsychores.2012.04.001. View

18.

Tieges Z, Mead G, Allerhand M, Duncan F, van Wijck F, Fitzsimons C . Sedentary behavior in the first year after stroke: a longitudinal cohort study with objective measures. Arch Phys Med Rehabil. 2014; 96(1):15-23. DOI: 10.1016/j.apmr.2014.08.015. View

19.

Go A, Mozaffarian D, Roger V, Benjamin E, Berry J, Blaha M . Heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation. 2013; 129(3):e28-e292. PMC: 5408159. DOI: 10.1161/01.cir.0000441139.02102.80. View

20.

Haskell W, Lee I, Pate R, Powell K, Blair S, Franklin B . Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation. 2007; 116(9):1081-93. DOI: 10.1161/CIRCULATIONAHA.107.185649. View