Realizing the Potential of Routine Viral Load Testing in Sub-Saharan Africa

Overview

Journal J Int AIDS Soc

Specialty Infectious Diseases

Date 2017 Nov 14

PMID 29130621

Citations 22

Authors

Wafaa M El-Sadr

Miriam Rabkin

John Nkengasong

Deborah L Birx

Affiliations

Soon will be listed here.

Citing Articles

The potential promise and pitfalls of point-of-care viral load monitoring to expedite HIV treatment decision-making in rural Uganda: a qualitative study.

Rosen J, Ddaaki W, Nakyanjo N, Chang L, Vo A, Zhao T BMC Health Serv Res. 2024; 24(1):1265.

PMID: 39434090 PMC: 11494746. DOI: 10.1186/s12913-024-11747-w.

Assessment of the effect of pre-conception care on preventing mother-to-child transmission of HIV in Nyeri County.

Ndapatani L, Mapesa J, Muchina E Pan Afr Med J. 2024; 47:144.

PMID: 38933429 PMC: 11204976. DOI: 10.11604/pamj.2024.47.144.37196.

Virological Suppression and its Predictors Among HIV/AIDS Patients on Antiretroviral Therapy in Ethiopia: Systematic Review and Meta-analysis.

Melak D, Bayou F, Yasin H, Zerga A, Wagaye B, Yeshanew Ayele F Open Forum Infect Dis. 2024; 11(4):ofae168.

PMID: 38654969 PMC: 11036161. DOI: 10.1093/ofid/ofae168.

"They test my blood to know how much blood is in my body": the untapped potential of promoting viral load literacy to support adherence and viral suppression among adolescents living with HIV.

Bernays S, Lariat J, Cowan F, Senzanje B, Willis N, Nenguke Z J Int AIDS Soc. 2023; 26(10):e26153.

PMID: 37880186 PMC: 10600064. DOI: 10.1002/jia2.26153.

Clinic-based SAMBA-II vs centralized laboratory viral load assays among HIV-1 infected children, adolescents and young adults in rural Zimbabwe: A randomized controlled trial.

Kouamou V, Machekano R, Mapangisana T, Maposhere C, Mutetwa R, Manasa J PLoS One. 2023; 18(2):e0281279.

PMID: 36787296 PMC: 9928130. DOI: 10.1371/journal.pone.0281279.

References

Bulage L, Ssewanyana I, Nankabirwa V, Nsubuga F, Kihembo C, Pande G . Factors Associated with Virological Non-suppression among HIV-Positive Patients on Antiretroviral Therapy in Uganda, August 2014-July 2015. BMC Infect Dis. 2017; 17(1):326. PMC: 5415758. DOI: 10.1186/s12879-017-2428-3. View

Peter T, Zeh C, Katz Z, Elbireer A, Alemayehu B, Vojnov L . Scaling up HIV viral load - lessons from the large-scale implementation of HIV early infant diagnosis and CD4 testing. J Int AIDS Soc. 2017; 20 Suppl 7. PMC: 5978645. DOI: 10.1002/jia2.25008. View

Nuwagaba-Biribonwoha H, Werq-Semo B, Abdallah A, Cunningham A, Gamaliel J, Mtunga S . Introducing a multi-site program for early diagnosis of HIV infection among HIV-exposed infants in Tanzania. BMC Pediatr. 2010; 10:44. PMC: 2907368. DOI: 10.1186/1471-2431-10-44. View

Jobanputra K, Parker L, Azih C, Okello V, Maphalala G, Kershberger B . Factors associated with virological failure and suppression after enhanced adherence counselling, in children, adolescents and adults on antiretroviral therapy for HIV in Swaziland. PLoS One. 2015; 10(2):e0116144. PMC: 4335028. DOI: 10.1371/journal.pone.0116144. View

Chatterjee A, Tripathi S, Gass R, Hamunime N, Panha S, Kiyaga C . Implementing services for Early Infant Diagnosis (EID) of HIV: a comparative descriptive analysis of national programs in four countries. BMC Public Health. 2011; 11:553. PMC: 3161890. DOI: 10.1186/1471-2458-11-553. View

Marcus R, Ferrand R, Kranzer K, Bekker L . The case for viral load testing in adolescents in resource-limited settings. J Int AIDS Soc. 2017; 20 Suppl 7. PMC: 5978738. DOI: 10.1002/jia2.25002. View

Essajee S, Bhairavabhotla R, Penazzato M, Kiragu K, Jani I, Carmona S . Scale-up of Early Infant HIV Diagnosis and Improving Access to Pediatric HIV Care in Global Plan Countries: Past and Future Perspectives. J Acquir Immune Defic Syndr. 2017; 75 Suppl 1:S51-S58. DOI: 10.1097/QAI.0000000000001319. View

Paterson D, Swindells S, Mohr J, BRESTER M, Vergis E, Squier C . Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Intern Med. 2000; 133(1):21-30. DOI: 10.7326/0003-4819-133-1-200007040-00004. View

Rangarajan S, Donn J, Giang L, Bui D, Hung Nguyen H, Tou P . Factors associated with HIV viral load suppression on antiretroviral therapy in Vietnam. J Virus Erad. 2016; 2(2):94-101. PMC: 4965252. View

10.

Drain P, Rousseau C . Point-of-care diagnostics: extending the laboratory network to reach the last mile. Curr Opin HIV AIDS. 2017; 12(2):175-181. PMC: 5287256. DOI: 10.1097/COH.0000000000000351. View

11.

Lecher S, Williams J, Fonjungo P, Kim A, Ellenberger D, Zhang G . Progress with Scale-Up of HIV Viral Load Monitoring - Seven Sub-Saharan African Countries, January 2015-June 2016. MMWR Morb Mortal Wkly Rep. 2016; 65(47):1332-1335. DOI: 10.15585/mmwr.mm6547a2. View

12.

Hsiao N, Stinson K, Myer L . Linkage of HIV-infected infants from diagnosis to antiretroviral therapy services across the Western Cape, South Africa. PLoS One. 2013; 8(2):e55308. PMC: 3566187. DOI: 10.1371/journal.pone.0055308. View

13.

El-Sadr W, Rabkin M, Nkengasong J, Birx D . Realizing the potential of routine viral load testing in sub-Saharan Africa. J Int AIDS Soc. 2017; 20 Suppl 7. PMC: 5978658. DOI: 10.1002/jia2.25010. View

14.

Ellman T, Alemayehu B, Abrams E, Arpadi S, Howard A, El-Sadr W . Selecting a viral load threshold for routine monitoring in resource-limited settings: optimizing individual health and population impact. J Int AIDS Soc. 2017; 20 Suppl 7. PMC: 5978659. DOI: 10.1002/jia2.25007. View

15.

Abrams E, Strasser S . 90-90-90--Charting a steady course to end the paediatric HIV epidemic. J Int AIDS Soc. 2015; 18(Suppl 6):20296. PMC: 4670839. DOI: 10.7448/IAS.18.7.20296. View

16.

McNairy M, El-Sadr W . The HIV care continuum: no partial credit given. AIDS. 2012; 26(14):1735-8. DOI: 10.1097/QAD.0b013e328355d67b. View

17.

Saito S, Duong Y, Metz M, Lee K, Patel H, Sleeman K . Returning HIV-1 viral load results to participant-selected health facilities in national Population-based HIV Impact Assessment (PHIA) household surveys in three sub-Saharan African Countries, 2015 to 2016. J Int AIDS Soc. 2017; 20 Suppl 7. PMC: 5978652. DOI: 10.1002/jia2.25004. View

18.

Arpadi S, Shiau S, De Gusmao E, Violari A . Routine viral load monitoring in HIV-infected infants and children in low- and middle-income countries: challenges and opportunities. J Int AIDS Soc. 2017; 20 Suppl 7. PMC: 5978643. DOI: 10.1002/jia2.25001. View

19.

Cahn P . Candidates for inclusion in a universal antiretroviral regimen: dolutegravir. Curr Opin HIV AIDS. 2017; 12(4):318-323. DOI: 10.1097/COH.0000000000000388. View

20.

Cohen M, Chen Y, McCauley M, Gamble T, Hosseinipour M, Kumarasamy N . Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011; 365(6):493-505. PMC: 3200068. DOI: 10.1056/NEJMoa1105243. View