A Systematic Review on Multiparametric MR Imaging in Prostate Cancer Detection

Overview

Journal Infect Agent Cancer

Publisher Biomed Central

Specialty Infectious Diseases

Date 2017 Nov 3

PMID 29093748

Citations 28

Authors

Roberta Fusco

Mario Sansone

Vincenza Granata

Sergio Venanzio Setola

Antonella Petrillo

Affiliations

Soon will be listed here.

Abstract

Background: Literature data suggest that multi-parametric Magnetic Resonance Imaging (MRI), including morphologic T2-weigthed images (T2-MRI) and functional approaches such as Dynamic Contrast Enhanced-MRI (DCE-MRI), Diffusion Weighted Imaging (DWI) and Magnetic Resonance Spectroscopic Imaging (MRSI), give an added value in the prostate cancer localization and local staging.

Methods: We performed a systematic review of literature about the role and the potentiality of morphological and functional MRI in prostate cancer, also in a multimodal / multiparametric approach, and we reported the diagnostic accuracy results for different imaging modalities and for different MR coil settings: endorectal coil (ERC) and phased array coil (PAC). Forest plots and receiver operating characteristic curves were performed. Risk of bias and the applicability at study level were calculated.

Results: Thirty three papers were identified for the systematic review. Sensitivity and specificity values were, respectively, for T2-MRI of 75% and of 60%, for DCE-MRI of 80% and of 72%, for MRSI of 89% and of 69%, for combined T2-MRI and DCE-MRI of 87% and of 46%, for combined T2-MRI and MRSI of 79% and of 57%, for combined T2-MRI, DWI and DCE-MRI of 81% and of 84%, and for combined MRSI and DCE-MRI of 83% and of 83%. For MRI studies performed with ERC we obtained a pooled sensitivity and specificity of 81% and of 66% while the pooled values for MRI studies performed with PAC were of 78% and of 64%, respectively (p>0.05 at McNemar test). No studies were excluded from the analysis based on the quality assessment.

Conclusions: ERC use yielded no additional benefit in terms of prostate cancer detection accuracy compared to multi-channel PAC use (71% versus 68%) while the use of additional functional imaging techniques (DCE-MRI, DWI and MRSI) in a multiparametric MRI protocol improves the accuracy of prostate cancer detection allowing both the early cure and the guidance of biopsy.

Citing Articles

Research progress on deep learning in magnetic resonance imaging-based diagnosis and treatment of prostate cancer: a review on the current status and perspectives.

He M, Cao Y, Chi C, Yang X, Ramin R, Wang S Front Oncol. 2023; 13:1189370.

PMID: 37546423 PMC: 10400334. DOI: 10.3389/fonc.2023.1189370.

Qualitative and semi-quantitative ultrasound assessment in delta and Omicron Covid-19 patients: data from high volume reference center.

Granata V, Fusco R, Villanacci A, Grassi F, Grassi R, Di Stefano F Infect Agent Cancer. 2023; 18(1):34.

PMID: 37245026 PMC: 10220348. DOI: 10.1186/s13027-023-00515-w.

Colorectal liver metastases patients prognostic assessment: prospects and limits of radiomics and radiogenomics.

Granata V, Fusco R, Setola S, Galdiero R, Maggialetti N, Patrone R Infect Agent Cancer. 2023; 18(1):18.

PMID: 36927442 PMC: 10018963. DOI: 10.1186/s13027-023-00495-x.

Diagnostic Performance Evaluation of Multiparametric Magnetic Resonance Imaging in the Detection of Prostate Cancer with Supervised Machine Learning Methods.

Nematollahi H, Moslehi M, Aminolroayaei F, Maleki M, Shahbazi-Gahrouei D Diagnostics (Basel). 2023; 13(4).

PMID: 36832294 PMC: 9956028. DOI: 10.3390/diagnostics13040806.

Risk Assessment and Cholangiocarcinoma: Diagnostic Management and Artificial Intelligence.

Granata V, Fusco R, De Muzio F, Cutolo C, Grassi F, Brunese M Biology (Basel). 2023; 12(2).

PMID: 36829492 PMC: 9952965. DOI: 10.3390/biology12020213.

References

Whitaker N, Glenn W, Sahrudin A, Orde M, Delprado W, Lawson J . Human papillomavirus and Epstein Barr virus in prostate cancer: Koilocytes indicate potential oncogenic influences of human papillomavirus in prostate cancer. Prostate. 2012; 73(3):236-41. DOI: 10.1002/pros.22562. View

Chen H, Sutedjo J, Wang L, Yin X . Prostate Cancer Magnetic Resonance Spectroscopy Imaging at 1.5 and 3.0 T: A Meta-Analysis. Technol Cancer Res Treat. 2016; 15(4):625-31. DOI: 10.1177/1533034616650779. View

Coakley F, Kurhanewicz J, Lu Y, Jones K, Swanson M, Chang S . Prostate cancer tumor volume: measurement with endorectal MR and MR spectroscopic imaging. Radiology. 2002; 223(1):91-7. DOI: 10.1148/radiol.2231010575. View

Yagci A, Ozari N, Aybek Z, Duzcan E . The value of diffusion-weighted MRI for prostate cancer detection and localization. Diagn Interv Radiol. 2010; 17(2):130-4. DOI: 10.4261/1305-3825.DIR.3399-10.1. View

Fusco R, Sansone M, Petrillo M, Setola S, Granata V, Botti G . Multiparametric MRI for prostate cancer detection: Preliminary results on quantitative analysis of dynamic contrast enhanced imaging, diffusion-weighted imaging and spectroscopy imaging. Magn Reson Imaging. 2016; 34(7):839-45. DOI: 10.1016/j.mri.2016.04.001. View

Cirillo S, Petracchini M, Della Monica P, Gallo T, Tartaglia V, Vestita E . Value of endorectal MRI and MRS in patients with elevated prostate-specific antigen levels and previous negative biopsies to localize peripheral zone tumours. Clin Radiol. 2008; 63(8):871-9. DOI: 10.1016/j.crad.2007.10.020. View

Loffroy R, Chevallier O, Moulin M, Favelier S, Genson P, Pottecher P . Current role of multiparametric magnetic resonance imaging for prostate cancer. Quant Imaging Med Surg. 2015; 5(5):754-64. PMC: 4671975. DOI: 10.3978/j.issn.2223-4292.2015.10.08. View

Margolis D . Multiparametric MRI for localized prostate cancer: lesion detection and staging. Biomed Res Int. 2014; 2014:684127. PMC: 4266765. DOI: 10.1155/2014/684127. View

Costa D, Yuan Q, Xi Y, Rofsky N, Lenkinski R, Lotan Y . Comparison of prostate cancer detection at 3-T MRI with and without an endorectal coil: A prospective, paired-patient study. Urol Oncol. 2016; 34(6):255.e7-255.e13. DOI: 10.1016/j.urolonc.2016.02.009. View

10.

Stamey T, McNeal J, Freiha F, Redwine E . Morphometric and clinical studies on 68 consecutive radical prostatectomies. J Urol. 1988; 139(6):1235-41. DOI: 10.1016/s0022-5347(17)42876-x. View

11.

Hegde J, Mulkern R, Panych L, Fennessy F, Fedorov A, Maier S . Multiparametric MRI of prostate cancer: an update on state-of-the-art techniques and their performance in detecting and localizing prostate cancer. J Magn Reson Imaging. 2013; 37(5):1035-54. PMC: 3741996. DOI: 10.1002/jmri.23860. View

12.

Bonekamp D, Jacobs M, El-Khouli R, Stoianovici D, Macura K . Advancements in MR imaging of the prostate: from diagnosis to interventions. Radiographics. 2011; 31(3):677-703. PMC: 3093638. DOI: 10.1148/rg.313105139. View

13.

Wang L, Zhang J, Schwartz L, Eisenberg H, Ishill N, Moskowitz C . Incremental value of multiplanar cross-referencing for prostate cancer staging with endorectal MRI. AJR Am J Roentgenol. 2006; 188(1):99-104. DOI: 10.2214/ajr.05.1783. View

14.

Sciarra A, Panebianco V, Salciccia S, Osimani M, Lisi D, Ciccariello M . Role of dynamic contrast-enhanced magnetic resonance (MR) imaging and proton MR spectroscopic imaging in the detection of local recurrence after radical prostatectomy for prostate cancer. Eur Urol. 2008; 54(3):589-600. DOI: 10.1016/j.eururo.2007.12.034. View

15.

Franiel T, Stephan C, Erbersdobler A, Dietz E, Maxeiner A, Hell N . Areas suspicious for prostate cancer: MR-guided biopsy in patients with at least one transrectal US-guided biopsy with a negative finding--multiparametric MR imaging for detection and biopsy planning. Radiology. 2011; 259(1):162-72. DOI: 10.1148/radiol.10101251. View

16.

Salerno J, Finelli A, Morash C, Morgan S, Power N, Schieda N . Multiparametric magnetic resonance imaging for pre-treatment local staging of prostate cancer: A Cancer Care Ontario clinical practice guideline. Can Urol Assoc J. 2016; 10(9-10):E332-E339. PMC: 5085920. DOI: 10.5489/cuaj.3823. View

17.

Kitajima K, Kaji Y, Fukabori Y, Yoshida K, Suganuma N, Sugimura K . Prostate cancer detection with 3 T MRI: comparison of diffusion-weighted imaging and dynamic contrast-enhanced MRI in combination with T2-weighted imaging. J Magn Reson Imaging. 2010; 31(3):625-31. DOI: 10.1002/jmri.22075. View

18.

Javali T, Dwivedi D, Kumar R, Jagannathan N, Thulkar S, Dinda A . Magnetic resonance spectroscopy imaging-directed transrectal ultrasound biopsy increases prostate cancer detection in men with prostate-specific antigen between 4-10 ng/mL and normal digital rectal examination. Int J Urol. 2013; 21(3):257-62. DOI: 10.1111/iju.12258. View

19.

Wang L, Mazaheri Y, Zhang J, Ishill N, Kuroiwa K, Hricak H . Assessment of biologic aggressiveness of prostate cancer: correlation of MR signal intensity with Gleason grade after radical prostatectomy. Radiology. 2007; 246(1):168-76. DOI: 10.1148/radiol.2461070057. View

20.

McNeal J, Villers A, Redwine E, Freiha F, Stamey T . Capsular penetration in prostate cancer. Significance for natural history and treatment. Am J Surg Pathol. 1990; 14(3):240-7. DOI: 10.1097/00000478-199003000-00005. View