Treatment of Keloid Scars Using Light-, Laser- and Energy-based Devices: a Contemporary Review of the Literature

Overview

Journal Lasers Med Sci

Publisher Springer

Date 2017 Oct 20

PMID 29047002

Citations 12

Authors

E Forbat

F R Ali

F Al-Niaimi

Affiliations

Soon will be listed here.

Abstract

Keloid scars are common and have a predilection for young, ethnic skin often with a family history. Keloids can be painful and pruritic and cause significant emotional distress when particularly visible or prominent. In this article, we review the evidence underlying the use of laser- and energy-based devices for treatment of keloid scars, either as monotherapy or in conjunction with other therapies such as corticosteroids, surgery and silicone gel in the treatment of keloid scars.

Citing Articles

Future Directions About Keloid Scars Based on Pathogenesis and Therapies.

Zhang G, Liu Z, Li Z, Xu Y Clin Cosmet Investig Dermatol. 2024; 17:2391-2408.

PMID: 39474263 PMC: 11520916. DOI: 10.2147/CCID.S470650.

Efficacy of a multimodal approach of laser therapy for earlobe keloids management in dark population.

Piccolo D, Crisman G, Conforti C, Fusco I, Bonan P Skin Res Technol. 2023; 29(11):e13502.

PMID: 38009015 PMC: 10591025. DOI: 10.1111/srt.13502.

Tissue-remodelling M2 Macrophages Recruits Matrix Metallo-proteinase-9 for Cryotherapy-induced Fibrotic Resolution during Keloid Treatment.

Lee Y, Kim S, Kim J, Kim J, Song S, Lee W Acta Derm Venereol. 2020; 100(17):adv00306.

PMID: 33073297 PMC: 9274924. DOI: 10.2340/00015555-3665.

The role of pharmacogenetics in keloid scar treatment: A literature review.

Searle T, Ali F, Al-Niaimi F Scars Burn Heal. 2020; 6:2059513120941704.

PMID: 32922964 PMC: 7446553. DOI: 10.1177/2059513120941704.

Keloids: a review of therapeutic management.

Ekstein S, Wyles S, Moran S, Meves A Int J Dermatol. 2020; 60(6):661-671.

PMID: 32905614 PMC: 7940466. DOI: 10.1111/ijd.15159.

References

Tenna S, Aveta A, Filoni A, Persichetti P . A new carbon dioxide laser combined with cyanoacrylate glue to treat earlobe keloids. Plast Reconstr Surg. 2012; 129(5):843e-844e. DOI: 10.1097/PRS.0b013e31824a6207. View

Yun J, Choi Y, Kim W, Lee G . Prevention of thyroidectomy scars in Asian adults using a 532-nm potassium titanyl phosphate laser. Dermatol Surg. 2011; 37(12):1747-53. DOI: 10.1111/j.1524-4725.2011.02128.x. View

Cassuto D, Scrimali L, Sirago P . Treatment of hypertrophic scars and keloids with an LBO laser (532 nm) and silicone gel sheeting. J Cosmet Laser Ther. 2010; 12(1):32-7. DOI: 10.3109/14764170903453846. View

Asilian A, Darougheh A, Shariati F . New combination of triamcinolone, 5-Fluorouracil, and pulsed-dye laser for treatment of keloid and hypertrophic scars. Dermatol Surg. 2006; 32(7):907-15. DOI: 10.1111/j.1524-4725.2006.32195.x. View

Cho S, Lee J, Lee S, Lee S, Bang D, Oh S . Efficacy and safety of 1064-nm Q-switched Nd:YAG laser with low fluence for keloids and hypertrophic scars. J Eur Acad Dermatol Venereol. 2010; 24(9):1070-4. DOI: 10.1111/j.1468-3083.2010.03593.x. View

Connell P, Harland C . Treatment of keloid scars with pulsed dye laser and intralesional steroid. J Cutan Laser Ther. 2001; 2(3):147-50. DOI: 10.1080/14628830050516407. View

Al-Mohamady A, Ibrahim S, Muhammad M . Pulsed dye laser versus long-pulsed Nd:YAG laser in the treatment of hypertrophic scars and keloid: A comparative randomized split-scar trial. J Cosmet Laser Ther. 2016; 18(4):208-12. DOI: 10.3109/14764172.2015.1114648. View

Niwa A, Mello A, Torezan L, Osorio N . Fractional photothermolysis for the treatment of hypertrophic scars: clinical experience of eight cases. Dermatol Surg. 2009; 35(5):773-7. DOI: 10.1111/j.1524-4725.2009.01127.x. View

Cheng E, Nowak K, Koch R . Effect of blended carbon dioxide and erbium:YAG laser energy on preauricular and ear lobule keloid fibroblast secretion of growth factors: a serum-free study. Arch Facial Plast Surg. 2001; 3(4):252-7. DOI: 10.1001/archfaci.3.4.252. View

10.

Bellew S, Weiss M, Weiss R . Comparison of intense pulsed light to 595-nm long-pulsed pulsed dye laser for treatment of hypertrophic surgical scars: a pilot study. J Drugs Dermatol. 2005; 4(4):448-52. View

11.

Garg G, Sao P, Khopkar U . Effect of carbon dioxide laser ablation followed by intralesional steroids on keloids. J Cutan Aesthet Surg. 2011; 4(1):2-6. PMC: 3081479. DOI: 10.4103/0974-2077.79176. View

12.

Tierney E, Mahmoud B, Srivastava D, Ozog D, Kouba D . Treatment of surgical scars with nonablative fractional laser versus pulsed dye laser: a randomized controlled trial. Dermatol Surg. 2009; 35(8):1172-80. DOI: 10.1111/j.1524-4725.2009.01085.x. View

13.

Cavalie M, Sillard L, Montaudie H, Bahadoran P, Lacour J, Passeron T . Treatment of keloids with laser-assisted topical steroid delivery: a retrospective study of 23 cases. Dermatol Ther. 2014; 28(2):74-8. DOI: 10.1111/dth.12187. View

14.

Koike S, Akaishi S, Nagashima Y, Dohi T, Hyakusoku H, Ogawa R . Nd:YAG Laser Treatment for Keloids and Hypertrophic Scars: An Analysis of 102 Cases. Plast Reconstr Surg Glob Open. 2015; 2(12):e272. PMC: 4292254. DOI: 10.1097/GOX.0000000000000231. View

15.

Juckett G, Hartman-Adams H . Management of keloids and hypertrophic scars. Am Fam Physician. 2009; 80(3):253-60. View

16.

Martin M, Collawn S . Combination treatment of CO2 fractional laser, pulsed dye laser, and triamcinolone acetonide injection for refractory keloid scars on the upper back. J Cosmet Laser Ther. 2013; 15(3):166-70. DOI: 10.3109/14764172.2013.780448. View

17.

Stephanides S, Rai S, August P, Ferguson J, Madan V . Treatment of refractory keloids with pulsed dye laser alone and with rotational pulsed dye laser and intralesional corticosteroids: A retrospective case series. Laser Ther. 2013; 20(4):279-86. PMC: 3799037. DOI: 10.5978/islsm.12-or-01. View

18.

Ang C, Tay Y, Kwok C . Retrospective analysis of earlobe keloids treated with the carbon dioxide laser ablation or cold steel debulking surgery. J Cosmet Laser Ther. 2013; 15(5):271-3. DOI: 10.3109/14764172.2013.769275. View

19.

Lin J, Warger W, Izikson L, Anderson R, Tannous Z . A prospective, randomized controlled trial on the efficacy of fractional photothermolysis on scar remodeling. Lasers Surg Med. 2011; 43(4):265-72. DOI: 10.1002/lsm.21061. View

20.

Conejo-Mir J, Corbi R, Linares M . Carbon dioxide laser ablation associated with interferon alfa-2b injections reduces the recurrence of keloids. J Am Acad Dermatol. 1998; 39(6):1039-40. DOI: 10.1016/s0190-9622(98)70295-6. View