Keloids: Current and Emerging Therapies

Overview

Journal Scars Burn Heal

Publisher Sage Publications

Date 2020 Aug 27

PMID 32844039

Citations 24

Authors

Nkemcho Ojeh

Ambadasu Bharatha

Uma Gaur

Andrew LeRoy Forde

Affiliations

Soon will be listed here.

Abstract

Lay Summary: Keloids are problematic scars that are difficult to treat and manage. The aetiopathogenesis of keloids is not clear; however, recent advances in molecular biology and genetics are beginning to shed light on the underlying mechanisms implicated in keloid scar formation which will hopefully lead to the development of treatment options for all keloid types. This review summarises current and emerging therapies.

Citing Articles

Analysis of factors affecting treatment adherence in patients with keloid disease.

Ge Q, Huang Y, Wu J, Ma J, He T, Zhang Q Arch Dermatol Res. 2025; 317(1):390.

PMID: 39937233 DOI: 10.1007/s00403-025-03849-0.

Wound Coverage, Adjuvant Treatments, and Surgical Outcomes for Major Keloid Scars: A Systematic Review and Meta-Analysis.

Cardenas D, Cincalir T, Dogaroiu A, Hinson C, Sink M, Bruce B Aesthet Surg J Open Forum. 2025; 7:ojae129.

PMID: 39935796 PMC: 11811037. DOI: 10.1093/asjof/ojae129.

Identification and validation of five ferroptosis-related molecular signatures in keloids based on multiple transcriptome data analysis.

Sun Z, Qin Y, Zhang X Front Mol Biosci. 2025; 11():1490745.

PMID: 39834787 PMC: 11743277. DOI: 10.3389/fmolb.2024.1490745.

The Efficacy of Botulinum Toxin Type A (BTA) in the Treatment of Hypertrophic Scars and Keloids: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Raslan E, Bakhamees B, Howsawi T, Alshmrani L, Alruwaili A, Alhashmi A Cureus. 2024; 16(10):e71161.

PMID: 39525161 PMC: 11548679. DOI: 10.7759/cureus.71161.

Logistic regression analysis of risk factors influencing postoperative keloid scar recurrence.

Hu X, Qiu T Am J Transl Res. 2024; 16(9):4849-4857.

PMID: 39398575 PMC: 11470296. DOI: 10.62347/CZYH2768.

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