» Articles » PMID: 29044265

A Comprehensive Review of the Health Perspectives of Resveratrol

Overview
Journal Food Funct
Date 2017 Oct 19
PMID 29044265
Citations 107
Authors
Affiliations
Soon will be listed here.
Abstract

Many natural products present in our diet, including flavonoids, can prevent the progression of cancer and other diseases. Resveratrol, a natural polyphenol present in various fruits and vegetables, plays an important role as a therapeutic and chemopreventive agent used in the treatment of various illnesses. It exhibits effects against different types of cancer through different pathways. It additionally exerts antidiabetic, anti-inflammatory, and anti-oxidant effects in a variety of cell types. Furthermore, the cardiovascular protective capacities of resveratrol are associated with multiple molecular targets and may lead to the development of novel therapeutic strategies for atherosclerosis, ischemia/reperfusion, metabolic syndrome, and heart failure. Accordingly, this article presents an overview of recent developments in the use of resveratrol for the prevention and treatment of different diseases along with various mechanisms. In addition, the present review summarizes the most recent literature pertaining to resveratrol as a chemotherapeutic agent against multiple diseases and provides an assessment of the potential of this natural compound as a complementary or alternative medicine.

Citing Articles

Effects of resveratrol supplementation on serum concentrations of plasminogen activator inhibitor-1, fibroblast growth factor 21, and adiponectin in patients with nonalcoholic fatty liver disease.

Farzin L, Mansouri E, Salehi S, Baker E, Amirkhizi F, Asghari S BMC Nutr. 2025; 11(1):36.

PMID: 39930480 PMC: 11809030. DOI: 10.1186/s40795-025-00997-4.


Development of a Water-Soluble Nanomicellar Formulation Loaded with Trans-Resveratrol Using Polyethylene Glycol Monostearate for the Treatment of Intracerebral Hemorrhage.

Banshoya K, Machida A, Kawamura S, Yamada T, Okada R, Kawamoto Y Pharmaceutics. 2024; 16(11).

PMID: 39598585 PMC: 11597214. DOI: 10.3390/pharmaceutics16111462.


Extracts from the leaves of knotweeds (Reynoutria spp.) have a stimulating effect on the germination and initial growth of wheat grains.

Sera B, Doshi P, Vechet L Naturwissenschaften. 2024; 111(6):61.

PMID: 39499314 PMC: 11538141. DOI: 10.1007/s00114-024-01946-0.


Targeting Gut Microbiota with Probiotics and Phenolic Compounds in the Treatment of Atherosclerosis: A Comprehensive Review.

Cruz Neto J, de Luna Freire M, de Albuquerque Lemos D, Ribeiro Alves R, de Farias Cardoso E, de Moura Balarini C Foods. 2024; 13(18).

PMID: 39335815 PMC: 11431284. DOI: 10.3390/foods13182886.


Rapid Synthesis and Evaluation of Resveratrol-Piperazine Cocrystals by Ultrasound and Microwave Methods.

Ionita S, Patrascu M, Soare E, Lincu D, Atkinson I, Rusu A Pharm Res. 2024; 41(9):1843-1853.

PMID: 39112777 DOI: 10.1007/s11095-024-03758-3.