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Cellular and Molecular Mechanisms of Drug Dependence

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Journal Science
Specialty Science
Date 1988 Nov 4
PMID 2903550
Citations 451
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Abstract

The molecular and cellular actions of three classes of abused drugs--opiates, psychostimulants, and ethanol--are reviewed in the context of behavioral studies of drug dependence. The immediate effects of drugs are compared to those observed after long-term exposure. A neurobiological basis for drug dependence is proposed from the linkage between the cellular and behavioral effects of these drugs.

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