G F Koob
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Explore the profile of G F Koob including associated specialties, affiliations and a list of published articles.
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431
Citations
19308
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Recent Articles
1.
Scarlata M, Keeley R, Carmack S, Tsai P, Vendruscolo J, Lu H, et al.
Addict Neurosci
. 2023 Jun;
1.
PMID: 37323812
Opioid use disorder (OUD) is defined as a compulsion to seek and take opioids, loss of control over intake and the development of a negative emotional state when access to...
2.
Moussawi K, Ortiz M, Gantz S, Tunstall B, Marchette R, Bonci A, et al.
Sci Adv
. 2020 Aug;
6(32):eabc0413.
PMID: 32821843
Intravenous drug self-administration is considered the "gold standard" model to investigate the neurobiology of drug addiction in rodents. However, its use in mice is limited by frequent complications of intravenous...
3.
Zallar L, Tunstall B, Richie C, Zhang Y, You Z, Gardner E, et al.
Int J Obes (Lond)
. 2018 Feb;
43(2):344-354.
PMID: 29453460
Background/objectives: Ghrelin, a stomach-derived hormone implicated in numerous behaviors including feeding, reward, stress, and addictive behaviors, acts by binding to the growth hormone secretagogue receptor (GHSR). Here, we present the...
4.
Lohoff F, Sorcher J, Rosen A, Mauro K, Fanelli R, Momenan R, et al.
Mol Psychiatry
. 2017 Aug;
23(9):1900-1910.
PMID: 28848234
Alcohol use disorder (AUD) is a common and chronic disorder with substantial effects on personal and public health. The underlying pathophysiology is poorly understood but strong evidence suggests significant roles...
5.
Aoun E, Jimenez V, Vendruscolo L, Walter N, Barbier E, Ferrulli A, et al.
Mol Psychiatry
. 2017 May;
23(6):1466-1473.
PMID: 28461696
Aldosterone regulates electrolyte and fluid homeostasis through binding to the mineralocorticoid receptors (MRs). Previous work provides evidence for a role of aldosterone in alcohol use disorders (AUDs). We tested the...
6.
Galinato M, Lockner J, Fannon-Pavlich M, Sobieraj J, Staples M, Somkuwar S, et al.
Mol Psychiatry
. 2017 Mar;
23(3):629-638.
PMID: 28348387
Adult neurogenesis in the dentate gyrus (DG) is strongly influenced by drug-taking behavior and may have a role in the etiology of drug-seeking behavior. However, mechanistic studies on the relationship...
7.
Sanna P, Kawamura T, Chen J, Koob G, Roberts A, Vendruscolo L, et al.
Transl Psychiatry
. 2016 Mar;
6:e760.
PMID: 26978742
The identification of new and more effective treatments for alcohol abuse remains a priority. Alcohol intake activates glucocorticoids, which have a key role in alcohol's reinforcing properties. Glucocorticoid effects are...
8.
Edwards S, Baynes B, Carmichael C, Zamora-Martinez E, Barrus M, Koob G, et al.
Transl Psychiatry
. 2013 Aug;
3:e296.
PMID: 23982628
Post-traumatic stress disorder (PTSD) and alcoholism are highly comorbid in humans and have partially overlapping symptomatic profiles. The aim of these studies was to examine the effects of traumatic stress...
9.
Tobey K, Walentiny D, Wiley J, Carroll F, Damaj M, Azar M, et al.
Psychopharmacology (Berl)
. 2012 Apr;
223(2):159-68.
PMID: 22526534
Rationale: Alleviating addiction to tobacco products could prevent millions of deaths. Investigating novel compounds selectively targeting α4β2 nAChRs hypothesized to have a key role in the rewarding effects of nicotine...
10.
Ali S, Onaivi E, Dodd P, Cadet J, Schenk S, Kuhar M, et al.
Curr Neuropharmacol
. 2011 Sep;
9(1):2-7.
PMID: 21886551
IDARS is an acronym for the International Drug Abuse Research Society. Apart from our scientific and educational purposes, we communicate information to the general and scientific community about substance abuse...