The Effect of Diabetes Mellitus Type I on Periodontal and Dental Status

Overview

Journal J Clin Diagn Res

Specialty General Medicine

Date 2017 Sep 13

PMID 28893034

Citations 10

Authors

Rokhsareh Sadeghi

Ferial Taleghani

Samira Mohammadi

Zahra Zohri

Affiliations

Soon will be listed here.

Abstract

Introduction: Diabetes mellitus type I is a chronic metabolic disease with an autoimmune origin. The initial manifestations mainly appear during childhood and its prevalence is on the rise in many countries. Some of the complications of diabetes mellitus are problems related to oro-dental structures and periodontal diseases.

Aim: The present study was undertaken to evaluate the relationship between diabetes mellitus type I and dental and periodontal status in Tehran, Iran.

Materials And Methods: This cross-sectional study was carried out on 50 patients with diabetes mellitus type I who were under treatment in the Diabetic Patients' Center in Tehran and 50 healthy individuals who did not have diabetes, all recruited from schools. The subjects were divided into two age groups of 6-12 and 13-18 years. In test group, HbA1c (glycosylated haemoglobin) level of the patients was collected from the medical records of Association of Diabetic Patients. To make sure that the control subjects did not suffer from diabetes mellitus, their blood glucose was measured with the Glucocard 01 blood glucose monitoring kit (GT-1920, Japan). The periodontal and dental status were assessed using dmft/DMFT (Decayed, Missing, Filled Permanent Teeth), GI (Gingival Index), PPD (Periodontal Pocket Depth), PI (Plaque Index) and CI (Calculus Index). The data obtained from each group were compared statistically using the Mann-Whitney test and Kruskal Wallis Test.

Results: There was increase in PPD, GI and DMFT values with aging, with no significant differences between the diabetic and non-diabetic groups. PI and DMFT not only increased with aging but also were higher in both age groups in patients with diabetes compared to healthy subjects (p<0.05). GI was higher only in the 13-18 year age group in diabetic patients (p<0.01). There was no relation between the HbA1c (glycosylated haemoglobin) level, and periodontal indices (p<0.09).

Conclusion: It appears that patients with diabetes mellitus type I are more susceptible to periodontal diseases and tooth loss and such problems might be aggravated with aging.

Citing Articles

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Assessment of Oral Health Status among Children with Type I Diabetes Mellitus: A Cross-sectional Study.

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Poor glycemic control impairs oral health in children with type 1 diabetes mellitus - a systematic review and meta-analysis.

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Oral Health Implications and Dental Management of Diabetic Children.

Davidopoulou S, Bitzeni-Nigdeli A, Archaki C, Arhakis A Int J Clin Pediatr Dent. 2023; 15(5):631-635.

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References

Patino Marin N, Loyola Rodriguez J, Medina Solis C, Pontigo Loyola A, Reyes Macias J, Ortega Rosado J . Caries, periodontal disease and tooth loss in patients with diabetes mellitus types 1 and 2. Acta Odontol Latinoam. 2009; 21(2):127-33. View

Moreira A, Passos I, Sampaio F, Soares M, Oliveira R . Flow rate, pH and calcium concentration of saliva of children and adolescents with type 1 diabetes mellitus. Braz J Med Biol Res. 2009; 42(8):707-11. DOI: 10.1590/s0100-879x2009005000006. View

Poplawska-Kita A, Siewko K, Szpak P, Krol B, Telejko B, Klimiuk P . Association between type 1 diabetes and periodontal health. Adv Med Sci. 2014; 59(1):126-31. DOI: 10.1016/j.advms.2014.01.002. View

Luczaj-Cepowicz E, Marczuk-Kolada G, Waszkiel D . Evaluation of periodontal status in young patients with insulin-dependent diabetes mellitus (type 1). Adv Med Sci. 2007; 51 Suppl 1:134-7. View

Ismail A, McGrath C, Yiu C . Oral health of children with type 1 diabetes mellitus: A systematic review. Diabetes Res Clin Pract. 2015; 108(3):369-81. DOI: 10.1016/j.diabres.2015.03.003. View

SILNESS J, Loe H . PERIODONTAL DISEASE IN PREGNANCY. II. CORRELATION BETWEEN ORAL HYGIENE AND PERIODONTAL CONDTION. Acta Odontol Scand. 1964; 22:121-35. DOI: 10.3109/00016356408993968. View

Kakade S, Shetiya S, Kakodkar P, Shirahatti R, Agrawal D . Periodontal status of type I diabetics compared to non-diabetic participants: a preliminary study. Ceylon Med J. 2014; 59(1):19-20. DOI: 10.4038/cmj.v59i1.5259. View

Gujjar K, Khadija H, Suleiman M, Amith H . Gingival health status of 2- to 15-year-old Benghazi children with type-I diabetes mellitus. J Dent Child (Chic). 2011; 78(2):96-101. View

. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2010; 33 Suppl 1:S62-9. PMC: 2797383. DOI: 10.2337/dc10-S062. View

10.

Rafatjou R, Razavi Z, Tayebi S, Khalili M, Farhadian M . Dental Health Status and Hygiene in Children and Adolescents with Type 1 Diabetes Mellitus. J Res Health Sci. 2016; 16(3):122-126. PMC: 7191025. View

11.

Siudikiene J, Maciulskiene V, Dobrovolskiene R, Nedzelskiene I . Oral hygiene in children with type I diabetes mellitus. Stomatologija. 2005; 7(1):24-7. View

12.

Zalewska A, Knas M, Kuzmiuk A, Waszkiewicz N, Niczyporuk M, Waszkiel D . Salivary innate defense system in type 1 diabetes mellitus in children with mixed and permanent dentition. Acta Odontol Scand. 2013; 71(6):1493-500. DOI: 10.3109/00016357.2013.773071. View

13.

TCHOBROUTSKY G . Relation of diabetic control to development of microvascular complications. Diabetologia. 1978; 15(3):143-52. DOI: 10.1007/BF00421230. View

14.

Ervasti T, Knuuttila M, Pohjamo L, Haukipuro K . Relation between control of diabetes and gingival bleeding. J Periodontol. 1985; 56(3):154-7. DOI: 10.1902/jop.1985.56.3.154. View

15.

Novaes Jr A, Pereira A, de MORAES N, Novaes A . Manifestations of insulin-dependent diabetes mellitus in the periodontium of young Brazilian patients. J Periodontol. 1991; 62(2):116-22. DOI: 10.1902/jop.1991.62.2.116. View

16.

de Pommereau V, Robert J, Brion M . Periodontal status in insulin-dependent diabetic adolescents. J Clin Periodontol. 1992; 19(9 Pt 1):628-32. DOI: 10.1111/j.1600-051x.1992.tb01710.x. View

17.

Aren G, Sepet E, Ozdemir D, Dinccag N, Guvener B, Firatli E . Periodontal health, salivary status, and metabolic control in children with type 1 diabetes mellitus. J Periodontol. 2004; 74(12):1789-95. DOI: 10.1902/jop.2003.74.12.1789. View

18.

Tagelsir A, Cauwels R, Van Aken S, Vanobbergen J, Martens L . Dental caries and dental care level (restorative index) in children with diabetes mellitus type 1. Int J Paediatr Dent. 2010; 21(1):13-22. DOI: 10.1111/j.1365-263X.2010.01094.x. View

19.

El-Tekeya M, El Tantawi M, Fetouh H, Mowafy E, Abo Khedr N . Caries risk indicators in children with type 1 diabetes mellitus in relation to metabolic control. Pediatr Dent. 2012; 34(7):510-6. View

20.

Grover H, Luthra S . Molecular mechanisms involved in the bidirectional relationship between diabetes mellitus and periodontal disease. J Indian Soc Periodontol. 2013; 17(3):292-301. PMC: 3768178. DOI: 10.4103/0972-124X.115642. View