Biomarkers in Solid Organ Transplantation
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Recipients of solid organs such as the kidney and heart are treated with standard immunosuppressive regimens, and personalized medicine has not yet reached the clinic for this patient population. Biomarkers potentially will allow treatment regimens to be adjusted, according to the needs of the individual patient. Biomarkers may reflect the degree of immunosuppression of the immune system, or they may reflect early damage to the transplanted organ.
Review: immunosuppression for the lung transplant patient.
Kotecha S, Ivulich S, Snell G J Thorac Dis. 2022; 13(11):6628-6644.
PMID: 34992841 PMC: 8662512. DOI: 10.21037/jtd-2021-11.
The Evolution of Lung Transplant Immunosuppression.
Ivulich S, Westall G, Dooley M, Snell G Drugs. 2018; 78(10):965-982.
PMID: 29915895 DOI: 10.1007/s40265-018-0930-6.
Biomarkers in solid organ transplantation.
van Gelder T Br J Clin Pharmacol. 2017; 83(12):2602-2604.
PMID: 28880407 PMC: 5698566. DOI: 10.1111/bcp.13391.