A Mouse Homeo Box Gene, Hox-1.5, and the Morphological Locus, Hd, Map to Within 1 CM on Chromosome 6

Overview

Journal Genetics

Publisher Oxford University Press

Specialty Genetics

Date 1987 Aug 1

PMID 2887485

Citations 16

Authors

B A Mock

L A DHoostelaere

R Matthai

K Huppi

Affiliations

Soon will be listed here.

Abstract

Mo-10, a homeo box-containing sequence in the Hox-1 complex of genes referred to as Hox-1.5, was found to be polymorphic in inbred and wild mice, and a strain distribution of three allelic forms of Hox-1.5 are reported. The position of Hox-1.5 was mapped in backcross experiments to within 1 cM of the hypodactyly locus on chromosome 6. This identifies the Hd mutation as a useful model for the examination of homeo box expression during mammalian development.

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