Ghrelin and Growth

Overview

Journal Endocr Dev

Publisher Karger

Specialties Endocrinology
Pediatrics

Date 2017 Sep 6

PMID 28873385

Citations 10

Authors

Reena Perchard

Peter E Clayton

Affiliations

Soon will be listed here.

Abstract

Ghrelin is a pleiotropic hormone, whose effect on growth hormone secretion, through the growth hormone secretagogue (GHS) receptor, is one of its many actions. Relationships between GHS receptor gene variants and human height, both in healthy individuals and in patients with growth disorders have been identified. These include constitutional delay in growth and puberty, idiopathic short stature, and isolated growth hormone deficiency. In this review, we provide an overview of the role of ghrelin in growth.

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