Metallic Biomaterials: Current Challenges and Opportunities

Overview

Journal Materials (Basel)

Publisher MDPI

Date 2017 Aug 5

PMID 28773240

Citations 107

Authors

Karthika Prasad

Olha Bazaka

Ming Chua

Madison Rochford

Liam Fedrick

Jordan Spoor

Richard Symes

Marcus Tieppo

Cameron Collins

Alex Cao

David Markwell

Kostya Ken Ostrikov

Kateryna Bazaka

Affiliations

Soon will be listed here.

Abstract

Metallic biomaterials are engineered systems designed to provide internal support to biological tissues and they are being used largely in joint replacements, dental implants, orthopaedic fixations and stents. Higher biomaterial usage is associated with an increased incidence of implant-related complications due to poor implant integration, inflammation, mechanical instability, necrosis and infections, and associated prolonged patient care, pain and loss of function. In this review, we will briefly explore major representatives of metallic biomaterials along with the key existing and emerging strategies for surface and bulk modification used to improve biointegration, mechanical strength and flexibility of biometals, and discuss their compatibility with the concept of 3D printing.

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