Picture Free Recall Performance Linked to the Brain's Structural Connectome

Overview

Journal Brain Behav

Specialty Psychology

Date 2017 Jul 22

PMID 28729929

Citations 2

Authors

David Coynel

Leo Gschwind

Matthias Fastenrath

Virginie Freytag

Annette Milnik

Klara Spalek

Andreas Papassotiropoulos

Dominique J-F de Quervain

Affiliations

Soon will be listed here.

Abstract

Introduction: Memory functions are highly variable between healthy humans. The neural correlates of this variability remain largely unknown.

Methods: Here, we investigated how differences in free recall performance are associated with DTI-based properties of the brain's structural connectome and with grey matter volumes in 664 healthy young individuals tested in the same MR scanner.

Results: Global structural connectivity, but not overall or regional grey matter volumes, positively correlated with recall performance. Moreover, a set of 22 inter-regional connections, including some with no previously reported relation to human memory, such as the connection between the temporal pole and the nucleus accumbens, explained 7.8% of phenotypic variance.

Conclusions: In conclusion, this large-scale study indicates that individual memory performance is associated with the level of structural brain connectivity.

Citing Articles

Sex-dependent differences in connectivity patterns are related to episodic memory recall.

Spalek K, Coynel D, de Quervain D, Milnik A Hum Brain Mapp. 2023; 44(17):5612-5623.

PMID: 37647201 PMC: 10619411. DOI: 10.1002/hbm.26465.

Picture free recall performance linked to the brain's structural connectome.

Coynel D, Gschwind L, Fastenrath M, Freytag V, Milnik A, Spalek K Brain Behav. 2017; 7(7):e00721.

PMID: 28729929 PMC: 5516597. DOI: 10.1002/brb3.721.

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