» Articles » PMID: 28620536

Factors Associated with Uterine Fibroid in Ghanaian Women Undergoing Pelvic Scans with Suspected Uterine Fibroid

Overview
Publisher Biomed Central
Date 2017 Jun 17
PMID 28620536
Citations 8
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Uterine fibroids are the most common benign tumours affecting premenopausal women and are often associated with considerable hospitalization and morbidity. Literature shows virtually no study concerning the quantification of the main factors associated with uterine fibroids in Ghanaian women. The purpose of this study was to assess the main factors associated with uterine fibroid among Ghanaian women presenting for ultrasound.

Method: A prospective cross-sectional study design was employed in this study. A total of two hundred and forty-four (244) women were consecutively evaluated from November 2011 to February 2012 using a 2-5 MHz curvilinear probe of Philips HD3 ultrasound machines at three centres in Accra using a trans-abdominal pelvic approach. Data was analysed with (SPSS) version 20.0 for windows, 2010; Chicago. The Pearson's Chi-square test was used to determine associations between selected demographic and gynaecological characteristics and uterine fibroid appearance. All tests were two-tailed and p-value of less than 0.05 was interpreted as significant.

Results: The range, mean and standard deviation (SD) of the patients' age were 14-54 years, 31.89 years and ± 7.92 respectively. Factors that associated significantly with uterine fibroid in Ghanaian women included obesity ( = 17.3, -value = 0.001), participant's age range ( = 47.4, -value = 0.001), parity ( = -10.169, -value = 0.001), and age at last delivery ( = 34.579, -value = 0.001).

Conclusion: Uterine fibroid was mainly associated with women of older age group of the reproductive age than the younger age categories and also associated more with women with without children compared to those with more children. Moreover, it associated more with obese patients and patient with late age at last delivery.

Citing Articles

Population-based study of the reproductive risk factors for transvaginal ultrasound diagnosed uterine fibroids in Nigerian women.

Adebamowo C, Adebamowo S Sci Rep. 2023; 13(1):18926.

PMID: 37919335 PMC: 10622570. DOI: 10.1038/s41598-023-44703-5.


Validation of self-report of uterine fibroid diagnosis using a transvaginal ultrasound scan.

Adebamowo C, Morhason-Bello I, Adebamowo S Sci Rep. 2023; 13(1):9091.

PMID: 37277479 PMC: 10241956. DOI: 10.1038/s41598-023-36313-y.


Age of first diagnosis and incidence rate of uterine fibroids in Ghana. A retrospective cohort study.

Edzie E, Dzefi-Tettey K, Brakohiapa E, Quarshie F, Ken-Amoah S, Cudjoe O PLoS One. 2023; 18(3):e0283201.

PMID: 36928541 PMC: 10019645. DOI: 10.1371/journal.pone.0283201.


Association between ESR1 rs2234693 single nucleotide polymorphism and uterine fibroids in Taiwanese premenopausal and postmenopausal women.

Tyan Y, Shen C, Tantoh D, Hsu S, Chou Y, Nfor O J Health Popul Nutr. 2023; 42(1):16.

PMID: 36890612 PMC: 9993586. DOI: 10.1186/s41043-023-00357-7.


Uterine fibroids - Causes, impact, treatment, and lens to the African perspective.

Sefah N, Ndebele S, Prince L, Korasare E, Agbleke M, Nkansah A Front Pharmacol. 2023; 13:1045783.

PMID: 36703761 PMC: 9871264. DOI: 10.3389/fphar.2022.1045783.


References
1.
Xu L, Wang Y, Collins C, Tang S . Urban health insurance reform and coverage in China using data from National Health Services Surveys in 1998 and 2003. BMC Health Serv Res. 2007; 7:37. PMC: 1828155. DOI: 10.1186/1472-6963-7-37. View

2.
Marshall L, Spiegelman D, Manson J, Goldman M, Barbieri R, Stampfer M . Risk of uterine leiomyomata among premenopausal women in relation to body size and cigarette smoking. Epidemiology. 1998; 9(5):511-7. View

3.
Sarkodie B, Botwe B, Ofori E . Uterine fibroid characteristics and sonographic pattern among Ghanaian females undergoing pelvic ultrasound scan: a study at 3-major centres. BMC Womens Health. 2016; 16:10. PMC: 4754812. DOI: 10.1186/s12905-016-0288-4. View

4.
Hodge J, Quade B, Rubin M, Stewart E, Dal Cin P, Morton C . Molecular and cytogenetic characterization of plexiform leiomyomata provide further evidence for genetic heterogeneity underlying uterine fibroids. Am J Pathol. 2008; 172(5):1403-10. PMC: 2329848. DOI: 10.2353/ajpath.2008.071102. View

5.
Schneider J, Bradlow H, Strain G, Levin J, Anderson K, Fishman J . Effects of obesity on estradiol metabolism: decreased formation of nonuterotropic metabolites. J Clin Endocrinol Metab. 1983; 56(5):973-8. DOI: 10.1210/jcem-56-5-973. View