Transition-Metal-Free and Oxidant-Free Cross-Coupling of Arylhydrazines with Disulfides: Base-Promoted Synthesis of Unsymmetrical Aryl Sulfides

Overview

Journal J Org Chem

Publisher American Chemical Society

Specialty Chemistry

Date 2017 Jun 16

PMID 28616985

Citations 9

Authors

Toshihide Taniguchi

Takuya Naka

Mitsutaka Imoto

Motonori Takeda

Takeo Nakai

Masatoshi Mihara

Takumi Mizuno

Akihiro Nomoto

Akiya Ogawa

Affiliations

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Abstract

A novel synthesis of unsymmetrical aryl sulfides, which requires no transition metal catalyst and no oxidant, was developed. This base-promoted cross-coupling reaction proceeded using arylhydrazines and 1 equiv amount of disulfides under inert gas conditions to afford the unsymmetrical aryl sulfides in good yields.

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