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Prosopagnosia: Current Perspectives

Overview
Journal Eye Brain
Publisher Dove Medical Press
Date 2017 May 26
PMID 28539812
Citations 36
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Abstract

Prosopagnosia is a selective visual agnosia characterized by the inability to recognize the identity of faces. There are both acquired forms secondary to brain damage and developmental forms without obvious structural lesions. In this review, we first discuss the diagnosis of acquired and developmental prosopagnosia, and the challenges present in the latter case. Second, we discuss the evidence regarding the selectivity of the prosopagnosic defect, particularly in relation to the recognition of other objects, written words (another visual object category requiring high expertise), and voices. Third, we summarize recent findings about the structural and functional basis of prosopagnosia from studies using magnetic resonance imaging, functional magnetic resonance imaging, and event-related potentials. Finally, we discuss recent attempts at rehabilitation of face recognition in prosopagnosia.

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References
1.
Shah P, Gaule A, Sowden S, Bird G, Cook R . The 20-item prosopagnosia index (PI20): a self-report instrument for identifying developmental prosopagnosia. R Soc Open Sci. 2015; 2(6):140343. PMC: 4632531. DOI: 10.1098/rsos.140343. View

2.
Avidan G, Tanzer M, Hadj-Bouziane F, Liu N, Ungerleider L, Behrmann M . Selective dissociation between core and extended regions of the face processing network in congenital prosopagnosia. Cereb Cortex. 2013; 24(6):1565-78. PMC: 4064011. DOI: 10.1093/cercor/bht007. View

3.
Farah M, Wilson K, Drain H, Tanaka J . The inverted face inversion effect in prosopagnosia: evidence for mandatory, face-specific perceptual mechanisms. Vision Res. 1995; 35(14):2089-93. DOI: 10.1016/0042-6989(94)00273-o. View

4.
Archer J, Hay D, Young A . Face processing in psychiatric conditions. Br J Clin Psychol. 1992; 31(1):45-61. DOI: 10.1111/j.2044-8260.1992.tb00967.x. View

5.
Duchaine B . Developmental prosopagnosia with normal configural processing. Neuroreport. 2000; 11(1):79-83. DOI: 10.1097/00001756-200001170-00016. View