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Two New Flavonoids from Artemisia Argyi with Their Anticoagulation Activities

Overview
Journal Nat Prod Res
Specialty Biology
Date 2017 May 26
PMID 28539062
Citations 16
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Abstract

A new flavone glycoside, eupatilin 7-O-β-d-glucopyranoside (1) and a new flavone, 5,6,2',4'-tetrahydroxy-7,5'-dimethoxyflavone (2), were isolated from Artemisia argyi. Their structures were unambiguously elucidated by extensive spectroscopic analysis. Both flavonoids were evaluated for in vitro anticoagulation activities. Compound 1 significantly extended thrombin time. Compound 2 had obvious effect in increasing prothrombin time.

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