Natural Leishmania (Viannia) Infections of Phlebotomines (Diptera: Psychodidae) Indicate Classical and Alternative Transmission Cycles of American Cutaneous Leishmaniasis in the Guiana Shield, Brazil

Overview

Journal Parasite

Specialty Parasitology

Date 2017 May 17

PMID 28508745

Citations 9

Authors

Adelson Alcimar Almeida de Souza

Iorlando da Rocha Barata

Maria das Gracas Soares Silva

Jose Aprigio Nunes Lima

Yara Lucia Lins Jennings

Edna Aoba Yassui Ishikawa

Ghislaine Prevot

Marine Ginouves

Fernando Tobias Silveira

Jeffrey Shaw

Thiago Vasconcelos Dos Santos

Affiliations

Soon will be listed here.

Abstract

From 1996 to 1999 multi-trapping methods (Center of Diseases Control, CDC) light traps, light-baited Shannon traps, and aspiration on tree bases) were used to study the phlebotomine fauna of the "Serra do Navio" region of the Brazilian State of Amapá, which is part of the Guiana Shield. Fifty-three species were identified among 8,685 captured individuals. The following species, associated with the transmission of American cutaneous leishmaniasis in Amazonian Brazil, were captured: Nyssomyia umbratilis (3,388), Psychodopygus squamiventris maripaensis (995), Ny. anduzei (550), Trichophoromyia ubiquitalis (400), Ny. whitmani (291), Ps. paraensis (116), and Bichromomyia flaviscutellata (50). Flagellate infections were detected in 45 flies. Of the 19 parasites isolated in vitro, 15 were Leishmania (Viannia) guyanensis (13 in Ny. umbratilis, 1 in Ny. whitmani, 1 in Ny. anduzei) and three were L. (V.) naiffi (2 in Ps. s. maripaensis, 1 in Ny. anduzei). The results indicate the participation of three phlebotomine species in the transmission of L. (V.) guyanensis and two species in that of L. (V.) naiffi, and show that the same phlebotomine species is involved in the transmission of different Leishmania (Viannia) species in the Guianan/Amazon region. A review of the literature together with the results of the present study, and other published and unpublished results, indicate that eight phlebotomine species potentially participate in the transmission of Leishmania (Viannia) naiffi in Amazonia.

Citing Articles

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Sanchez Uzcategui Y, Silveira F, de Morais T, Furtado R, Vasconcelos Dos Santos T, Povoa M Microorganisms. 2024; 12(4).

PMID: 38674753 PMC: 11051748. DOI: 10.3390/microorganisms12040809.

Leishmania (Viannia) naiffi Lainson & Shaw 1989.

Motta Cantanhede L, Cupolillo E Parasit Vectors. 2023; 16(1):194.

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Vadmal G, Glidden C, Han B, Carvalho B, Castellanos A, Mordecai E PLoS Negl Trop Dis. 2023; 17(2):e0010749.

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Outbreak of Cutaneous Leishmaniasis among military personnel in French Guiana, 2020: Clinical, phylogenetic, individual and environmental aspects.

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Further insights into the eco-epidemiology of American cutaneous leishmaniasis in the Belem metropolitan region, Pará State, Brazil.

Goncalves L, Vasconcelos Dos Santos T, Campos M, Lima L, Ishikawa E, Silveira F Rev Soc Bras Med Trop. 2020; 53:e20200255.

PMID: 33331607 PMC: 7747830. DOI: 10.1590/0037-8682-0255-2020.

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