Natural Leishmania (Viannia) Spp. Infections in Phlebotomine Sand Flies (Diptera: Psychodidae) from the Brazilian Amazon Region Reveal New Putative Transmission Cycles of American Cutaneous Leishmaniasis

Overview

Journal Parasite

Specialty Parasitology

Date 2016 May 29

PMID 27235194

Citations 13

Authors

Adelson Alcimar Almeida de Souza

Thiago Vasconcelos Dos Santos

Yara Lucia Lins Jennings

Edna Aoba Yassui Ishikawa

Iorlando da Rocha Barata

Maria das Gracas Soares Silva

Jose Aprigio Nunes Lima

Jeffrey Shaw

Ralph Lainson

Fernando Tobias Silveira

Affiliations

Soon will be listed here.

Abstract

In Amazonian Brazil the etiological agents of American cutaneous leishmaniasis (ACL) belong to at least seven Leishmania species but little is known about the putative phlebotomine sand fly vectors in different biomes. In 2002-2003 a survey of the phlebotomine fauna was undertaken in the "Floresta Nacional do Tapajós", Belterra municipality, in the lower Amazon region, western Pará State, Brazil, where we recently confirmed the presence of a putative hybrid parasite, L. (V.) guyanensis × L. (V.) shawi shawi. Sand flies were collected from Centers for Disease Control (CDC) light traps, Shannon traps and by aspiration on tree bases. Females were dissected and attempts to isolate any flagellate infections were made by inoculating homogenized midguts into Difco B(45) medium. Isolates were characterized by monoclonal antibodies and isoenzyme electrophoresis. A total of 9,704 sand flies, belonging to 68 species or subspecies, were collected. Infections were found in the following sand flies: L. (V.) naiffi with Psychodopygus hirsutus hirsutus (1) and Ps. davisi (2); and L. (V.) shawi shawi with Nyssomyia whitmani (3) and Lutzomyia gomezi (1). These results provide strong evidence of new putative transmission cycles for L. (V.) naiffi and L. (V.) s. shawi.

Citing Articles

Leishmania (Viannia) naiffi Lainson & Shaw 1989.

Motta Cantanhede L, Cupolillo E Parasit Vectors. 2023; 16(1):194.

PMID: 37291682 PMC: 10251559. DOI: 10.1186/s13071-023-05814-0.

First Report of an Asymptomatic Infection Using a Nasal Swab in Amazon, Brazil.

Oliveira L, Nascimento L, Santos F, Takamatsu J, Sanchez L, Santos W Int J Environ Res Public Health. 2022; 19(10).

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Molecular tools confirm natural Leishmania (Viannia) guyanensis/L. (V.) shawi hybrids causing cutaneous leishmaniasis in the Amazon region of Brazil.

Lima A, Gomes C, Tomokane T, Campos M, Zampieri R, Jorge C Genet Mol Biol. 2021; 44(2):e20200123.

PMID: 33949621 PMC: 8108439. DOI: 10.1590/1678-4685-GMB-2020-0123.

An overview of the sandfly fauna (Diptera: Psychodidae) followed by the detection of Leishmania DNA and blood meal identification in the state of Acre, Amazonian Brazil.

de Araujo-Pereira T, Pita-Pereira D, Baia-Gomes S, Boite M, Silva F, Pinto I Mem Inst Oswaldo Cruz. 2020; 115:e200157.

PMID: 33206821 PMC: 7668085. DOI: 10.1590/0074-02760200157.

Vertical stratification of sand fly diversity in relation to natural infections of Leishmania sp. and blood-meal sources in Jamari National Forest, Rondônia State, Brazil.

Leao P, Junior A, de Paulo P, Carvalho L, Souza A, da Silva M Parasit Vectors. 2020; 13(1):422.

PMID: 32807221 PMC: 7433131. DOI: 10.1186/s13071-020-04295-9.

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