» Articles » PMID: 28506301

Diffuse Non-midline Glioma with H3F3A K27M Mutation: a Prognostic and Treatment Dilemma

Overview
Publisher Biomed Central
Specialty Neurology
Date 2017 May 17
PMID 28506301
Citations 25
Authors
Affiliations
Soon will be listed here.
Citing Articles

Molecular and Pathological Features of Paediatric High-Grade Gliomas.

Blasco-Santana L, Colmenero I Int J Mol Sci. 2024; 25(15).

PMID: 39126064 PMC: 11312892. DOI: 10.3390/ijms25158498.


Neuroradiological, genetic and clinical characteristics of histone H3 K27-mutant diffuse midline gliomas in the Kansai Molecular Diagnosis Network for CNS Tumors (Kansai Network): multicenter retrospective cohort.

Hayashi N, Fukai J, Nakatogawa H, Kawaji H, Yoshioka E, Kodama Y Acta Neuropathol Commun. 2024; 12(1):120.

PMID: 39061104 PMC: 11282756. DOI: 10.1186/s40478-024-01808-w.


Diffuse hemispheric glioma with H3 p.K28M (K27M) mutation: Unusual non-midline presentation of diffuse midline glioma, H3 K27M-altered?.

Donev K, Sundararajan V, Johnson D, Balan J, Chambers M, Paulson V J Neuropathol Exp Neurol. 2024; 83(5):357-364.

PMID: 38447592 PMC: 11029465. DOI: 10.1093/jnen/nlae018.


Selective DRD2 antagonist and ClpP agonist ONC201 in a recurrent non-midline H3 K27M-mutant glioma cohort.

Odia Y, Hall M, Cloughesy T, Wen P, Arrillaga-Romany I, Daghistani D Neuro Oncol. 2024; 26(Supplement_2):S165-S172.

PMID: 38386699 PMC: 11066928. DOI: 10.1093/neuonc/noae021.


Does H3K27M Mutation Impact Survival Outcome of High-Grade Spinal Cord Astrocytoma?.

Zhang F, Cheng L, Ding Z, Wang S, Zhao X, Zhao Z Neurospine. 2024; 20(4):1480-1489.

PMID: 38171314 PMC: 10762395. DOI: 10.14245/ns.2346650.325.


References
1.
Louis D, Ohgaki H, Wiestler O, Cavenee W, Burger P, Jouvet A . The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007; 114(2):97-109. PMC: 1929165. DOI: 10.1007/s00401-007-0243-4. View

2.
Schwartzentruber J, Korshunov A, Liu X, Jones D, Pfaff E, Jacob K . Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature. 2012; 482(7384):226-31. DOI: 10.1038/nature10833. View

3.
Sturm D, Witt H, Hovestadt V, Khuong-Quang D, Jones D, Konermann C . Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell. 2012; 22(4):425-37. DOI: 10.1016/j.ccr.2012.08.024. View

4.
Wu G, Diaz A, Paugh B, Rankin S, Ju B, Li Y . The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma. Nat Genet. 2014; 46(5):444-450. PMC: 4056452. DOI: 10.1038/ng.2938. View

5.
Nguyen A, Colin C, Nanni-Metellus I, Padovani L, Maurage C, Varlet P . Evidence for BRAF V600E and H3F3A K27M double mutations in paediatric glial and glioneuronal tumours. Neuropathol Appl Neurobiol. 2014; 41(3):403-8. DOI: 10.1111/nan.12196. View