Human Chorionic Gonadotropin: The Pregnancy Hormone and More

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2017 May 16

PMID 28505106

Citations 14

Authors

Charalampos Theofanakis

Petros Drakakis

Alexandros Besharat

Dimitrios Loutradis

Affiliations

Soon will be listed here.

Abstract

To thoroughly review the uses of human chorionic gonadotropin (hCG) related to the process of reproduction and also assess new, non-traditional theories. Review of the international literature and research studies. hCG and its receptor, LH/CGR, are expressed in numerous sites of the reproductive tract, both in gonadal and extra-goanadal tissues, promoting oocyte maturation, fertilization, implantation and early embryo development. Moreover, hCG seems to have a potential role as an anti-rejection agent in solid organ transplantation. Future research needs to focus extensively on the functions of hCG and its receptor LH/CGR, in an effort to reveal known, as well as unknown clinical potentials.

Citing Articles

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Li J, Zhu X, Zhu W, Li L, Wei H, Zhang S Animals (Basel). 2024; 14(22).

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Twelve Hours Post-Injection Serum Human Chorionic Gonadotropin and Body Mass Index Predicts Fertilization Oocyte Maturation Rate: A Cross-Sectional Study.

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Sun X, Zhu H, Zhang C, Ilboudo J, Zhao J, Ma C J Anim Sci. 2023; 101.

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He X, Duan J, Ji Y, Zhao L, Jiang H, Jiang Y Comput Struct Biotechnol J. 2022; 20:6503-6511.

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