The Binding Characteristics of the Cytochrome C Iron

Overview

Journal Biochem J

Specialty Biochemistry

Date 1988 Oct 1

PMID 2848510

Citations 7

Authors

A SCHEJTER

B Plotkin

Affiliations

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Abstract

A comparison of the binding properties of myoglobin and cytochrome c shows that the latter, in the reduced state, has an unusually large affinity for ligands, including thioethers. This explains the outstanding stability of the methionine-iron bond of ferrous cytochrome c, and results from the intrinsic ability of the cytochrome c iron to delocalize its electrons into orbitals of the sixth axial ligand.

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