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» Articles » PMID: 28475229

Nomenclature and Definition in Asymmetric Regional Body Overgrowth

Overview
Journal Am J Med Genet A
Specialty Genetics
Date 2017 May 6
PMID 28475229
Citations 26
Authors
Jennifer M Kalish
Leslie G Biesecker
Frederic Brioude
Matthew A Deardorff
Alessandra Di Cesare-Merlone
Todd Druley
Giovanni B Ferrero
Pablo Lapunzina
Lidia Larizza
Saskia Maas
Marina Macchiaiolo
Eamonn R Maher
Silvia Maitz
Julian A Martinez-Agosto
Alessandro Mussa
Peter Robinson
Silvia Russo
Angelo Selicorni
Raoul C Hennekam
Affiliations
Soon will be listed here.
Abstract

We designate a novel term "isolated lateralized overgrowth" (ILO) for the findings previously described as "isolated hemihypertrophy" and "isolated hemihyperplasia." ILO is defined as lateralized overgrowth in the absence of a recognized pattern of malformations, dysplasia, or morphologic variants. ILO is likely genetically heterogeneous. Further study is required to determine more of the underlying genetic etiologies and potential associations with currently unrecognized patterns of malformation.

Citing Articles

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Progressive vascular tumor in infant: A case report and literature review of PIK3CA vascular malformation.

Medina A, Zima L, Atkinson A, Menon N, Bhattacharjee M, Bonfante E Childs Nerv Syst. 2024; 40(4):1005-1010.

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Investigation of 11p15.5 Methylation Defects Associated with Beckwith-Wiedemann Spectrum and Embryonic Tumor Risk in Lateralized Overgrowth Patients.

Tuysuz B, Bozlak S, Alkaya D, Ocak S, Kasap B, Sunamak Cifci E Cancers (Basel). 2023; 15(6).

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Performance Metrics of the Scoring System for the Diagnosis of the Beckwith-Wiedemann Spectrum (BWSp) and Its Correlation with Cancer Development.

Luca M, Carli D, Cardaropoli S, Milani D, Cocchi G, Leoni C Cancers (Basel). 2023; 15(3).

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Lateralized overgrowth as a guiding sign of abdominal neoplasms for pediatric orthopedic surgeons.

Parada-Avendano I, Salvador H, Garcia R, Martorell-Sampol L, Fontecha C, Torner-Rubies F Jt Dis Relat Surg. 2023; 34(1):3-8.

PMID: 36700257 PMC: 9903098. DOI: 10.52312/jdrs.2023.903.

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