The Effect of Ultrasound-guided Compression Immediately After Transrectal Ultrasound-guided Prostate Biopsy on Postbiopsy Bleeding: a Randomized Controlled Pilot Study

Overview

Journal Int Urol Nephrol

Publisher Springer

Specialty Nephrology

Date 2017 May 6

PMID 28474311

Citations 4

Authors

Bong Hee Park

Jung Im Kim

Sang Rak Bae

Yong Seok Lee

Sung Hak Kang

Chang Hee Han

Affiliations

Soon will be listed here.

Abstract

Purpose: To evaluate whether ultrasound-guided compression performed immediately after transrectal ultrasound (TRUS)-guided prostate biopsy decreases bleeding complications.

Methods: We prospectively evaluated a total of 148 consecutive patients who underwent TRUS-guided prostate biopsy between March 2015 and July 2016. Systematic 12-core prostate biopsy was performed in all patients. Of these, 100 patients were randomly assigned to one of two groups: the compression group (n = 50) underwent TRUS-guided compression on bleeding biopsy tracts immediately after prostate biopsy, while the non-compression group (n = 50) underwent TRUS-guided prostate biopsy alone. The incidence rate and duration of hematuria, hematospermia, and rectal bleeding were compared between the two groups.

Results: The incidence rates of hematuria and hematospermia were not significantly different between the two groups (60 vs. 64%, p = 0.68; 22 vs. 30%, p = 0.362, respectively, for compression vs. non-compression group). The rectal bleeding incidence was significantly lower in the compression group as compared to the non-compression group (20 vs. 44%, p = 0.01). However, there were no significant differences in the median duration of hematuria, hematospermia, or rectal bleeding between the two groups (2, 8, and 2 days vs. 2, 10, and 1 days, p > 0.05, respectively, for compression vs. non-compression group). TRUS-guided compression [p = 0.004, odds ratio (OR) 0.25] and patient age (p = 0.013, OR 0.93) were significantly protective against the occurrence of rectal bleeding after prostate biopsy in multivariable analysis.

Conclusions: Although it has no impact on other complications, ultrasound-guided compression on bleeding biopsy tracts performed immediately after TRUS-guided prostate biopsy is an effective and practical method to treat or decrease rectal bleeding.

Citing Articles

The effect of heated lidocaine gel on pain reduction during transrectal ultrasound-guided prostate biopsy: a randomized-controlled study.

Jung J, Moon H, Kim J, Bae S, Han C, Park B Int Urol Nephrol. 2021; 53(12):2437-2443.

PMID: 34591227 DOI: 10.1007/s11255-021-03006-2.

Endoscopic Therapy in the Management of Patients With Severe Rectal Bleeding Following Transrectal Ultrasound-Guided Prostate Biopsy: A Case-Based Systematic Review.

Malik A, Ishtiaq R, Goraya M, Inayat F, Gaduputi V J Investig Med High Impact Case Rep. 2021; 9:23247096211013206.

PMID: 33969720 PMC: 8113366. DOI: 10.1177/23247096211013206.

Hemostatic effect and psychological impact of an oxidized regenerated cellulose patch after transrectal ultrasound-guided prostate biopsy: A prospective and retrospective study.

Park J, Kim J, Bae S, Lee Y, Han C, Kang S Medicine (Baltimore). 2019; 98(20):e15623.

PMID: 31096472 PMC: 6531163. DOI: 10.1097/MD.0000000000015623.

The management of rectal bleeding following transrectal prostate biopsy: A review of the current literature.

Quinlan M, Bolton D, Casey R Can Urol Assoc J. 2017; 12(3):E146-E153.

PMID: 29283091 PMC: 5869041. DOI: 10.5489/cuaj.4660.

References

Peyromaure M, Ravery V, Messas A, Toublanc M, Boccon-Gibod L, Boccon-Gibod L . Pain and morbidity of an extensive prostate 10-biopsy protocol: a prospective study in 289 patients. J Urol. 2001; 167(1):218-21. View

Kilciler M, Erdemir F, Demir E, Guven O, Avci A . The effect of rectal Foley catheterization on rectal bleeding rates after transrectal ultrasound-guided prostate biopsy. J Vasc Interv Radiol. 2008; 19(9):1344-6. DOI: 10.1016/j.jvir.2008.06.005. View

Hodge K, McNeal J, Terris M, Stamey T . Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate. J Urol. 1989; 142(1):71-4; discussion 74-5. DOI: 10.1016/s0022-5347(17)38664-0. View

Ozveren B, Turkeri L . Massive rectal bleeding after prostate biopsy controlled by endoclipping in a patient using acetylsalicylic acid. Can Urol Assoc J. 2013; 7(5-6):E442-4. PMC: 3699096. DOI: 10.5489/cuaj.1390. View

Lee G, Attar K, Laniado M, Karim O . Safety and detailed patterns of morbidity of transrectal ultrasound guided needle biopsy of prostate in a urologist-led unit. Int Urol Nephrol. 2006; 38(2):281-5. DOI: 10.1007/s11255-006-6671-6. View

Bjurlin M, Wysock J, Taneja S . Optimization of prostate biopsy: review of technique and complications. Urol Clin North Am. 2014; 41(2):299-313. PMC: 4151475. DOI: 10.1016/j.ucl.2014.01.011. View

Shen P, Zhu Y, Wei W, Li Y, Yang J, Li Y . The results of transperineal versus transrectal prostate biopsy: a systematic review and meta-analysis. Asian J Androl. 2011; 14(2):310-5. PMC: 3735101. DOI: 10.1038/aja.2011.130. View

Park B, Kim S . Transrectal ultrasound performed immediately after prostate biopsy: imaging features and ultrasound-guided compression to bleeding biopsy tract. Acta Radiol. 2007; 48(2):232-7. DOI: 10.1080/02841850601080457. View

Loeb S, Vellekoop A, Ahmed H, Catto J, Emberton M, Nam R . Systematic review of complications of prostate biopsy. Eur Urol. 2013; 64(6):876-92. DOI: 10.1016/j.eururo.2013.05.049. View

10.

Zaytoun O, Anil T, Moussa A, Jianbo L, Fareed K, Stephen Jones J . Morbidity of prostate biopsy after simplified versus complex preparation protocols: assessment of risk factors. Urology. 2011; 77(4):910-4. DOI: 10.1016/j.urology.2010.12.033. View

11.

Halliwell O, Yadegafar G, Lane C, Dewbury K . Transrectal ultrasound-guided biopsy of the prostate: aspirin increases the incidence of minor bleeding complications. Clin Radiol. 2008; 63(5):557-61. DOI: 10.1016/j.crad.2007.09.014. View

12.

Kariotis I, Philippou P, Volanis D, Serafetinides E, Delakas D . Safety of ultrasound-guided transrectal extended prostate biopsy in patients receiving low-dose aspirin. Int Braz J Urol. 2010; 36(3):308-16. DOI: 10.1590/s1677-55382010000300007. View

13.

Wachsberg R . Transrectal color Doppler sonographically guided compression to treat active extravasation after transrectal prostate biopsy. AJR Am J Roentgenol. 2004; 183(6):1706-7. DOI: 10.2214/ajr.183.6.01831706. View

14.

Lovat L . Age related changes in gut physiology and nutritional status. Gut. 1996; 38(3):306-9. PMC: 1383055. DOI: 10.1136/gut.38.3.306. View

15.

Lee S, Chen S, Ho C, Chang P, Chen C, Tsui K . Risk factors associated with transrectal ultrasound guided prostate needle biopsy in patients with prostate cancer. Chang Gung Med J. 2009; 32(6):623-7. View

16.

Raber M, Scattoni V, Roscigno M, Deho F, Briganti A, Salonia A . Topical prilocaine-lidocaine cream combined with peripheral nerve block improves pain control in prostatic biopsy: results from a prospective randomized trial. Eur Urol. 2007; 53(5):967-73. DOI: 10.1016/j.eururo.2007.09.005. View

17.

Giannarini G, Mogorovich A, Valent F, Morelli G, De Maria M, Manassero F . Continuing or discontinuing low-dose aspirin before transrectal prostate biopsy: results of a prospective randomized trial. Urology. 2007; 70(3):501-5. DOI: 10.1016/j.urology.2007.04.016. View

18.

Eichler K, Hempel S, Wilby J, Myers L, Bachmann L, Kleijnen J . Diagnostic value of systematic biopsy methods in the investigation of prostate cancer: a systematic review. J Urol. 2006; 175(5):1605-12. DOI: 10.1016/S0022-5347(05)00957-2. View

19.

Addla S, Adeyoju A, Wemyss-Holden G, Neilson D . Local anaesthetic for transrectal ultrasound-guided prostate biopsy: a prospective, randomized, double blind, placebo-controlled study. Eur Urol. 2003; 43(5):441-3. DOI: 10.1016/s0302-2838(03)00104-0. View

20.

Jesus C, Correa L, Padovani C . Complications and risk factors in transrectal ultrasound-guided prostate biopsies. Sao Paulo Med J. 2006; 124(4):198-202. PMC: 11065365. DOI: 10.1590/s1516-31802006000400005. View