Wearable Smart Sensor Systems Integrated on Soft Contact Lenses for Wireless Ocular Diagnostics

Overview

Journal Nat Commun

Specialty Biology

Date 2017 Apr 28

PMID 28447604

Citations 196

Authors

Joohee Kim

Minji Kim

Mi-Sun Lee

Kukjoo Kim

Sangyoon Ji

Yun-Tae Kim

Jihun Park

Kyungmin Na

Kwi-Hyun Bae

Hong Kyun Kim

Franklin Bien

Chang Young Lee

Jang-Ung Park

Affiliations

Soon will be listed here.

Abstract

Wearable contact lenses which can monitor physiological parameters have attracted substantial interests due to the capability of direct detection of biomarkers contained in body fluids. However, previously reported contact lens sensors can only monitor a single analyte at a time. Furthermore, such ocular contact lenses generally obstruct the field of vision of the subject. Here, we developed a multifunctional contact lens sensor that alleviates some of these limitations since it was developed on an actual ocular contact lens. It was also designed to monitor glucose within tears, as well as intraocular pressure using the resistance and capacitance of the electronic device. Furthermore, in-vivo and in-vitro tests using a live rabbit and bovine eyeball demonstrated its reliable operation. Our developed contact lens sensor can measure the glucose level in tear fluid and intraocular pressure simultaneously but yet independently based on different electrical responses.

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