MTORC1 Signaling in Hepatic Lipid Metabolism

Overview

Journal Protein Cell

Publisher Oxford University Press

Specialties Biochemistry
Cell Biology

Date 2017 Apr 24

PMID 28434145

Citations 83

Authors

Jinbo Han

Yiguo Wang

Affiliations

Soon will be listed here.

Abstract

The mechanistic target of rapamycin (mTOR) signaling pathway regulates many metabolic and physiological processes in different organs or tissues. Dysregulation of mTOR signaling has been implicated in many human diseases including obesity, diabetes, cancer, fatty liver diseases, and neuronal disorders. Here we review recent progress in understanding how mTORC1 (mTOR complex 1) signaling regulates lipid metabolism in the liver.

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