Anesthetic-Related Neurotoxicity and Neuroimaging in Children: A Call for Conversation
Overview
Affiliations
Each year millions of young children undergo procedures requiring sedation or general anesthesia. An increasing proportion of the anesthetics used are provided to optimize diagnostic imaging studies such as magnetic resonance imaging. Concern regarding the neurotoxicity of sedatives and anesthetics has prompted the US Food and Drug Administration to change labeling of anesthetics and sedative agents warning against repeated or prolonged exposure in young children. This review aims to summarize the risk of anesthesia in children with an emphasis on anesthetic-related neurotoxicity, acknowledge the value of pediatric neuroimaging, and address this call for conversation.
Neurofibromatosis Type 1-Associated Optic Pathway Gliomas: Current Challenges and Future Prospects.
Tang Y, Gutmann D Cancer Manag Res. 2023; 15:667-681.
PMID: 37465080 PMC: 10351533. DOI: 10.2147/CMAR.S362678.
Pediatric Elbow Dislocations and Associated Fractures.
Lewallen L, Elliott M, Mcintosh A, Ho C Children (Basel). 2023; 10(6).
PMID: 37371225 PMC: 10297433. DOI: 10.3390/children10060993.
Biazar G, Soltanipour S, Mohammadzadeh Jouryabi A, Imantalab V, Nabi B, Sorouri Z Anesth Pain Med. 2022; 11(5):e118098.
PMID: 35127460 PMC: 8802414. DOI: 10.5812/aapm.118098.
Michali-Stolarska M, Tukiendorf A, Zacharzewska-Gondek A, Jackow-Nowicka J, Chrzanowska J, Trybek G J Clin Med. 2021; 10(19).
PMID: 34640616 PMC: 8509364. DOI: 10.3390/jcm10194598.
Agomelatine Attenuates Isoflurane-Induced Inflammation and Damage in Brain Endothelial Cells.
Cheng F, Chang H, Yan F, Yang A, Liu J, Liu Y Drug Des Devel Ther. 2020; 14:5589-5598.
PMID: 33376303 PMC: 7755371. DOI: 10.2147/DDDT.S281582.