Randall P Flick
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Explore the profile of Randall P Flick including associated specialties, affiliations and a list of published articles.
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Recent Articles
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Ing C, Warner D, Sun L, Flick R, Davidson A, Vutskits L, et al.
Anesthesiology
. 2022 Jan;
136(3):500-512.
PMID: 35015802
Anesthetic agents disrupt neurodevelopment in animal models, but evidence in humans is mixed. The morphologic and behavioral changes observed across many species predicted that deficits should be seen in humans,...
3.
Laporta M, Sprung J, Fejedelem C, Henning D, Weaver A, Hanson A, et al.
J Autism Dev Disord
. 2021 Oct;
52(10):4301-4310.
PMID: 34618293
This study tested the hypothesis that exposure of children prior to their third birthday to procedures requiring general anesthesia is associated with an increased incidence of autism spectrum disorder (ASD)...
4.
Shi Y, Dykhoff H, Guevara L, Sangaralingham L, Schroeder D, Flick R, et al.
Br J Anaesth
. 2021 Sep;
127(5):722-728.
PMID: 34503832
Background: Children's exposure to anaesthesia has been associated with risk of developing attention-deficit/hyperactivity disorder (ADHD). The goal of this study was to determine if selected patient characteristics moderate the association...
5.
Lee H, Byon H, Kim N, Gleich S, Flick R, Lee J
Sci Rep
. 2021 Mar;
11(1):5981.
PMID: 33727626
Upper respiratory tract infection (URI) symptoms are known to increase perioperative respiratory adverse events (PRAEs) in children undergoing general anaesthesia. General anaesthesia per se also induces atelectasis, which may worsen...
6.
Shi Y, Schulte P, Hanson A, Zaccariello M, Hu D, Crow S, et al.
BMC Pediatr
. 2020 Nov;
20(1):510.
PMID: 33158434
Background: To develop and evaluate machine learning algorithms to ascertain attention-deficit/hyperactivity (ADHD) and learning disability (LD) using diagnostic codes in the medical record. Method: Diagnoses of ADHD and LD were...
7.
Warner D, Hu D, Zaccariello M, Schroeder D, Hanson A, Wilder R, et al.
Anesth Analg
. 2020 Sep;
133(1):160-167.
PMID: 32932391
Background: Two prior population-based (children born in Olmsted County, MN), retrospective cohort studies both found that multiple exposures to anesthesia before age 3 were associated with a significant increase in...
8.
Zaccariello M, Frank R, Lee M, Kirsch A, Schroeder D, Hanson A, et al.
Br J Anaesth
. 2019 Apr;
122(5):671-681.
PMID: 30982593
Background: We hypothesised that exposure to multiple, but not single, procedures requiring general anaesthesia before age 3 yr is associated with a specific pattern of deficits in processing speed and...
9.
Warner D, Chelonis J, Paule M, Frank R, Lee M, Zaccariello M, et al.
Br J Anaesth
. 2019 Mar;
122(4):470-479.
PMID: 30857603
Background: It is not known whether the neurotoxicity produced by anaesthetics administered to young animals can also occur in children. Exposure of infant macaques to ketamine impairs performance in selected...
10.
Warner D, Zaccariello M, Katusic S, Schroeder D, Hanson A, Schulte P, et al.
Anesthesiology
. 2018 Apr;
129(1):89-105.
PMID: 29672337
Background: Few studies of how exposure of children to anesthesia may affect neurodevelopment employ comprehensive neuropsychological assessments. This study tested the hypothesis that exposure to multiple, but not single, procedures...