» Articles » PMID: 28360463

Prevalence of Hypersensitivity and Allergic Bronchopulmonary Aspergillosis in Patients with Bronchial Asthma at a Tertiary Care Center in North India

Overview
Journal Lung India
Specialty Pulmonary Medicine
Date 2017 Apr 1
PMID 28360463
Citations 6
Authors
Affiliations
Soon will be listed here.
Abstract

Background: The prevalence of hypersensitivity (AH) and allergic bronchopulmonary aspergillosis (ABPA) has been variably reported. Systematic data regarding sensitization and ABPA are lacking from this part of the country.

Objectives: The aim of this study was to evaluate the prevalence of AH and ABPA in Uttar Pradesh.

Setting And Design: This was prospective observational study. All patients attending outpatient Department of Pulmonary Medicine of our institute were included in the study.

Subjects And Methods: Consecutive asthmatic patients underwent screening for ABPA using skin test (AST). Those showing a positive response to AST were further evaluated for ABPA.

Results: During the study, 350 patients (192 males, 158 females, mean ± standard deviation age: 38.3 ± 12.8) were screened with AST. One hundred and twenty-three patients (35.1%) were tested positive for AST and 21.7% of patients were diagnosed as ABPA.

Conclusions: A high prevalence rate of ABPA was observed at our chest clinic. Although comparable with published data from other tertiary centers, it does not represent the true prevalence rates in asthmatics because of high chances of referral bias.

Citing Articles

Clinicomycological Study of the Spectrum of Pulmonary Aspergillosis at a Tertiary Care Hospital in Central India.

Krishna A, Keche A, Tg R, Das P Cureus. 2024; 16(3):e56147.

PMID: 38618367 PMC: 11015873. DOI: 10.7759/cureus.56147.


Prevalence of Aspergillus sensitization and Allergic Bronchopulmonary Aspergillosis in bronchial asthma: A systematic review of Indian studies.

Agarwal R, Muthu V, Sehgal I, Dhooria S, Prasad K, Soundappan K Lung India. 2023; 40(6):527-536.

PMID: 37961961 PMC: 10723202. DOI: 10.4103/lungindia.lungindia_69_23.


"Allergic bronchopulmonary aspergillosis misdiagnosed as smear negative pulmonary tuberculosis; a retrospective study from Pakistan".

Iqbal N, Sheikh M, Jabeen K, Awan S, Irfan M Ann Med Surg (Lond). 2021; 72:103045.

PMID: 34815860 PMC: 8591471. DOI: 10.1016/j.amsu.2021.103045.


Correlation of asthma severity, IgE level, and spirometry results with HRCT findings in allergic bronchopulmonary aspergillosis.

Neyaz Z, Hashim Z, Kumar S, Nath A, Khan A, Mohindro N Indian J Radiol Imaging. 2020; 30(2):163-169.

PMID: 33100683 PMC: 7546303. DOI: 10.4103/ijri.IJRI_443_19.


Allergic bronchopulmonary aspergillosis.

Agarwal R, Sehgal I, Dhooria S, Muthu V, Prasad K, Bal A Indian J Med Res. 2020; 151(6):529-549.

PMID: 32719226 PMC: 7602921. DOI: 10.4103/ijmr.IJMR_1187_19.


References
1.
Denning D, ODriscoll B, Hogaboam C, Bowyer P, Niven R . The link between fungi and severe asthma: a summary of the evidence. Eur Respir J. 2006; 27(3):615-26. DOI: 10.1183/09031936.06.00074705. View

2.
Greenberger P . Allergic bronchopulmonary aspergillosis and fungoses. Clin Chest Med. 1988; 9(4):599-608. View

3.
Rosenberg M, Patterson R, Mintzer R, COOPER B, Roberts M, Harris K . Clinical and immunologic criteria for the diagnosis of allergic bronchopulmonary aspergillosis. Ann Intern Med. 1977; 86(4):405-14. DOI: 10.7326/0003-4819-86-4-405. View

4.
Agrawal S, Pearce N, Ebrahim S . Prevalence and risk factors for self-reported asthma in an adult Indian population: a cross-sectional survey. Int J Tuberc Lung Dis. 2013; 17(2):275-82. PMC: 4284294. DOI: 10.5588/ijtld.12.0438. View

5.
Agarwal R, Noel V, Aggarwal A, Gupta D, Chakrabarti A . Clinical significance of Aspergillus sensitisation in bronchial asthma. Mycoses. 2011; 54(5):e531-8. DOI: 10.1111/j.1439-0507.2010.01971.x. View