Allergic Bronchopulmonary Aspergillosis

Overview

Journal Indian J Med Res

Specialty General Medicine

Date 2020 Jul 29

PMID 32719226

Citations 40

Authors

Ritesh Agarwal

Inderpaul S Sehgal

Sahajal Dhooria

Valliappan Muthu

Kuruswamy T Prasad

Amanjit Bal

Ashutosh N Aggarwal

Arunaloke Chakrabarti

Affiliations

Soon will be listed here.

Abstract

Allergic bronchopulmonary aspergillosis (ABPA) is an inflammatory disease caused by immunologic reactions initiated against Aspergillus fumigatus colonizing the airways of patients with asthma and cystic fibrosis. The common manifestations include treatment-resistant asthma, transient and fleeting pulmonary opacities and bronchiectasis. It is believed that globally there are about five million cases of ABPA, with India alone accounting for about 1.4 million cases. The occurrence of ABPA among asthmatic patients in special clinics may be as high as 13 per cent. Thus, a high degree of suspicion for ABPA should be entertained while treating a patient with bronchial asthma, particularly in specialized clinics. Early diagnosis and appropriate treatment can delay (or even prevent) the onset of bronchiectasis, which suggests that all patients of bronchial asthma should be screened for ABPA, especially in chest clinics. The current review summarizes the recent advances in the pathogenesis, diagnosis and management of ABPA.

Citing Articles

High level of initial Aspergillus fumigatus-specific IgE links increased risk of exacerbation in allergic bronchopulmonary aspergillosis patients.

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Distribution and Epidemiological Characteristics of Clinical Isolates of in a Hospital from 2021 to 2023: A Retrospective Study.

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Chronic pulmonary aspergillosis in tea population of Assam.

Selvasekhar A, Nath R, Gogoi G, Borah P PLoS Negl Trop Dis. 2025; 19(1):e0012756.

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A multidimensional grading system for ABPA treatment escalation within the first year: The HEID score.

Pingan Z, Yanliang M, Xi C, Yifan M, Luyang Y, Moqin Z World Allergy Organ J. 2024; 17(12):100996.

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Xie C, Yang J, Gul A, Li Y, Zhang R, Yalikun M Front Immunol. 2024; 15:1478624.

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