Risk Factors Involved in Orofacial Cleft Predisposition - Review

Overview

Journal Open Med (Wars)

Specialty General Medicine

Date 2017 Mar 30

PMID 28352691

Citations 10

Authors

Agata Kawalec

Kamil Nelke

Krystyna Pawlas

Hanna Gerber

Affiliations

Soon will be listed here.

Abstract

Clefts that occur in children are a special topic. Avoiding risk factors, and also an early diagnosis of cleft possibility can result in minimizing or avoiding them. If on the other hand when clefts occur they require a long-term, multistage specialized treatment. Etiology of clefts seems to be related to many factors. Factors such as genetic, environmental, geographic and even race factors are important. Identification of risk factors can lead to prevention and prophylactic behaviors in order to minimize its occurrence. Exposure to environmental factors at home and work that lead to cleft predisposition should not be disregarded. It seems that before planning a family it would be wise to consult with doctors of different specializations, especially in high-risk families with cleft history in order to analyze previous lifestyle. Clefts are very common in hereditary facial malformations and are causing a lot of other irregularities in the head and neck region. In this paper after a brief papers review authors present socio-geographic, environmental and also work place related factors that are influencing pregnant women condition and should be taken under serious consideration.

Citing Articles

Risk Factors for Nonsyndromic Orofacial Clefts Among Saudi Children.

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Orofacial Cleft and Its Association with Consanguineous Marriage and Other Risk Factors: A Case-control Study from a Tertiary Care Hospital in Jammu Province.

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Neurodevelopmental disorders in children with cleft lip and palate: a systematic review.

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Prenatal exposure to antibiotics and the risk of orofacial clefts: a protocol for a systematic review and meta-analysis.

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Orofacial Clefts and Maternal Risk Factors: A Population-Based Case-Control Study.

Santoro M, Mezzasalma L, Coi A, Pierini A Children (Basel). 2024; 11(7).

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