» Articles » PMID: 28299213

Cervical Spinal Cord Compression: A Rare Presentation of Hepatocellular Carcinoma

Overview
Publisher Wiley
Specialty Gastroenterology
Date 2017 Mar 17
PMID 28299213
Citations 2
Authors
Affiliations
Soon will be listed here.
Abstract

Hepatocellular carcinoma (HCC) is the most common primary malignancy of liver. Distant metastasis to various organs is well known. Skeletal metastasis is also reported to various locations. Vertebral metastasis has been reported mostly to thoracic spine. However, cervical spinal cord involvement leading to cord compression has been reported very rarely in literature. We present a case of 58-year-old male with liver cirrhosis presenting as neck pain. Further work-up revealed metastatic HCC to cervical spinal cord resulting in acute cord compression. Patient has been treated with neurosurgical intervention.

Citing Articles

Rare Site Hepatocellular Carcinoma Metastasis.

Boldo E, Santafe A, Mayol A, Lozoya R, Coret A, Escribano D J Hepatocell Carcinoma. 2020; 7:39-44.

PMID: 32274362 PMC: 7104197. DOI: 10.2147/JHC.S238963.


Hepatocellular carcinoma presenting as spinal cord compression in Native Americans with controlled hepatitis C: two case reports.

Liaukovich M, Wu S, Yoon S, Schaffer J, Wang J J Med Case Rep. 2018; 12(1):282.

PMID: 30268151 PMC: 6164177. DOI: 10.1186/s13256-018-1807-8.

References
1.
EDMONDSON H, STEINER P . Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsies. Cancer. 1954; 7(3):462-503. DOI: 10.1002/1097-0142(195405)7:3<462::aid-cncr2820070308>3.0.co;2-e. View

2.
Zhang D, Xu W, Liu T, Yin H, Yang X, Wu Z . Surgery and prognostic factors of patients with epidural spinal cord compression caused by hepatocellular carcinoma metastases: retrospective study of 36 patients in a single center. Spine (Phila Pa 1976). 2013; 38(17):E1090-5. DOI: 10.1097/BRS.0b013e3182983bf8. View

3.
Yang W, Yeo W, Leung S, Chan Y, Johnson P, Metreweli C . MRI and CT of metastatic hepatocellular carcinoma causing spinal cord compression. Clin Radiol. 1997; 52(10):755-60. DOI: 10.1016/s0009-9260(97)80154-7. View

4.
BATSON O . THE FUNCTION OF THE VERTEBRAL VEINS AND THEIR ROLE IN THE SPREAD OF METASTASES. Ann Surg. 1940; 112(1):138-49. PMC: 1387927. DOI: 10.1097/00000658-194007000-00016. View

5.
Hwang S, Lee J, Lee J, Hong S, Lee M, Chun H . Hepatocellular Carcinoma with Cervical Spine and Pelvic Bone Metastases Presenting as Unknown Primary Neoplasm. Korean J Gastroenterol. 2015; 66(1):50-4. DOI: 10.4166/kjg.2015.66.1.50. View