Comparison of Axial Length, Corneal Curvature, and Anterior Chamber Depth Measurements of 2 Recently Introduced Devices to a Known Biometer

Purpose: Evaluate agreement and repeatability of axial length (AL), corneal curvature, and anterior chamber depth measurements of 2 new devices, 1 using Scheimpflug technology combined with partial coherence interferometry (Pentacam AXL) and 1 using swept-source optical coherence tomography (IOL Master 700) to a widely used optical biometer (IOL Master 500).

Design: Prospective, instrument reliability analysis.

Methods: This study was conducted in the Department of Ophthalmology at Goethe-University, Frankfurt, Germany. Seventy-nine eyes in 79 patients were measured with the IOL Master 500, the IOL Master 700, and with the Pentacam AXL. All eyes were measured twice with each device. The results were statistically compared using Bland-Altman plots. Outcome measures included AL, corneal curvature, and the measurement of anterior chamber depth.

Results: The Bland-Altman analysis of axial length measurements with the IOL Master 500 and IOL Master 700 showed a mean difference of 0.008 mm between the 2 devices, with a coefficient of repeatability (COR) of 0.044 (P = .05). For measurements with the IOL Master 500 and Pentacam AXL, a mean difference of 0.026 mm and COR of 0.055 (P = .75) was found. For measurements with Pentacam AXL and IOL Master 700, a mean difference of -0.019 mm and COR of 0.052 (P = .06) was found. In terms of repeatability, there was no significant difference in measurement of any variable with any device. Vector analysis showed no significant difference for corneal astigmatism measurements (P = .84).

Conclusion: There was no statistically significant difference in compared biometric parameters performed with all 3 devices.