The Genus Carissa: An Ethnopharmacological, Phytochemical and Pharmacological Review

Overview

Journal Nat Prod Bioprospect

Publisher Springer

Specialty Biology

Date 2017 Mar 1

PMID 28243901

Citations 16

Authors

Joseph Sakah Kaunda

Ying-Jun Zhang

Affiliations

Soon will be listed here.

Abstract

Carissa L. is a genus of the family Apocynaceae, with about 36 species as evergreen shrubs or small trees native to tropical and subtropical regions of Africa, Asia and Oceania. Most of Carissa plants have been employed and utilized in traditional medicine for various ailments, such as headache, chest complains, rheumatism, oedema, gonorrhoea, syphilis, rabies. So far, only nine Carissa species have been phytochemically studied, which led to the identification of 123 compounds including terpenes, flavonoids, lignans, sterols, simple phenolic compounds, fatty acids and esters, and so on. Pharmacological studies on Carissa species have also indicated various bioactive potentials. This review covers the peer-reviewed articles between 1954 and 2016, retrieved from Pubmed, ScienceDirect, SciFinder, Wikipedia and Baidu, using "Carissa" as search term ("all fields") and with no specific time frame set for search. Fifteen important medicinal or ornamental Carissa species were selected and summarized on their botanical characteristics, geographical distribution, traditional uses, phytochemistry, and pharmacological activities.

Citing Articles

Antimicrobial, antioxidant and cytotoxic activities of the leaf and stem extracts of Carissa bispinosa used for dental health care.

Shekwa W, Maliehe T, Masoko P BMC Complement Med Ther. 2023; 23(1):462.

PMID: 38102607 PMC: 10722736. DOI: 10.1186/s12906-023-04308-x.

Phytonutritional and Sensorial Assessment of a Novel Functional Beverage Formulated from an Underutilized Fruit of L.

Mamoona T, Rafique N, Khan M, Ahmad K, Bashir S, Shah T ACS Omega. 2023; 8(36):32643-32655.

PMID: 37720775 PMC: 10500662. DOI: 10.1021/acsomega.3c03386.

Ethnomedicinal Uses, Phytochemistry, and Anticancer Potentials of African Medicinal Fruits: A Comprehensive Review.

Fakudze N, Sarbadhikary P, George B, Abrahamse H Pharmaceuticals (Basel). 2023; 16(8).

PMID: 37631032 PMC: 10458058. DOI: 10.3390/ph16081117.

Antiproliferative Effects and Phytochemical Characterization of ((Forssk) Vahl) and (Eckyl and Zeyh) Extracts.

Muruthi C, Ngugi M, Runo S, Mwitari P J Evid Based Integr Med. 2023; 28:2515690X231187711.

PMID: 37489007 PMC: 10387709. DOI: 10.1177/2515690X231187711.

Human Lung Cancer (A549) Cell Line Cytotoxicity and Anti- Activity of Leaves: A Study Supported by UPLC-ESI-MS/MS Metabolites Profiling and Molecular Docking.

Orabi M, Alqahtani O, Alyami B, Abdullah Al Awadh A, Abdel-Sattar E, Matsunami K Pharmaceuticals (Basel). 2022; 15(12).

PMID: 36559012 PMC: 9784246. DOI: 10.3390/ph15121561.

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