The Testis-specific Phosphoglycerate Kinase Gene Pgk-2 is a Recruited Retroposon

Overview

Journal Mol Cell Biol

Specialty Cell Biology

Date 1987 Sep 1

PMID 2823118

Citations 60

Authors

P H Boer

C N Adra

Y F Lau

M W McBurney

Affiliations

Soon will be listed here.

Abstract

In both humans and mice, two genes encode phosphoglycerate kinase, a key enzyme in the glycolytic pathway. The pgk-1 gene is expressed in all somatic cells, is located on the X chromosome, and contains 10 introns. The pgk-2 gene is expressed only in sperm cells, is located on an autosome, and has no introns. The nucleotide sequence of the pgk-2 gene suggests that it arose from pgk-1 more than 100 million years ago by RNA-mediated gene duplication. The pgk-2 gene may, then, be a transcribed retroposon. Thus, gene duplication by retroposition may have been used as a mechanism for evolutionary diversification.

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References

Clark B, Collins K, Gandy M, Webb A, Auron P . Genomic sequence for human prointerleukin 1 beta: possible evolution from a reverse transcribed prointerleukin 1 alpha gene. Nucleic Acids Res. 1986; 14(20):7897-914. PMC: 311823. DOI: 10.1093/nar/14.20.7897. View

Vandeberg J, Cooper D, Close P . Mammalian testis phosphoglycerate kinase. Nat New Biol. 1973; 243(123):48-50. View

Graham F, Van Der Eb A . A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology. 1973; 52(2):456-67. DOI: 10.1016/0042-6822(73)90341-3. View

SANGER F, Nicklen S, Coulson A . DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A. 1977; 74(12):5463-7. PMC: 431765. DOI: 10.1073/pnas.74.12.5463. View

Eicher E, Cherry M, Flaherty L . Autosomal phosphoglycerate kinase linked to mouse major histocompatibility complex. Mol Gen Genet. 1978; 158(3):225-8. DOI: 10.1007/BF00267193. View

Birnboim H, DOLY J . A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res. 1979; 7(6):1513-23. PMC: 342324. DOI: 10.1093/nar/7.6.1513. View

Lee C, Niesel D, Pegoraro B, Erickson R . Immunological and structural relatedness of isozymes and genetic variants of 3-phosphoglycerate kinase from the mouse. J Biol Chem. 1980; 255(6):2590-5. View

Auffray C, Rougeon F . Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA. Eur J Biochem. 1980; 107(2):303-14. DOI: 10.1111/j.1432-1033.1980.tb06030.x. View

Bucher T, Bender W, Fundele R, Hofner H, Linke I . Quantitative evaluation of electrophoretic allo-and isozyme patterns. FEBS Lett. 1980; 115(2):319-24. DOI: 10.1016/0014-5793(80)81197-5. View

10.

Corden J, Wasylyk B, Buchwalder A, Sassone-Corsi P, Kedinger C, Chambon P . Promoter sequences of eukaryotic protein-coding genes. Science. 1980; 209(4463):1406-14. DOI: 10.1126/science.6251548. View

11.

Mulligan R, Berg P . Expression of a bacterial gene in mammalian cells. Science. 1980; 209(4463):1422-7. DOI: 10.1126/science.6251549. View

12.

Jeffreys A, Harris S . Processes of gene duplication. Nature. 1982; 296(5852):9-10. DOI: 10.1038/296009a0. View

13.

Southern P, Berg P . Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. J Mol Appl Genet. 1982; 1(4):327-41. View

14.

Rogers J . Retroposons defined. Nature. 1983; 301(5900):460. DOI: 10.1038/301460e0. View

15.

Gold B, Fujimoto H, Kramer J, Erickson R, Hecht N . Haploid accumulation and translational control of phosphoglycerate kinase-2 messenger RNA during mouse spermatogenesis. Dev Biol. 1983; 98(2):392-9. DOI: 10.1016/0012-1606(83)90368-8. View

16.

Feinberg A, Vogelstein B . A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem. 1983; 132(1):6-13. DOI: 10.1016/0003-2697(83)90418-9. View

17.

Gubler U, HOFFMAN B . A simple and very efficient method for generating cDNA libraries. Gene. 1983; 25(2-3):263-9. DOI: 10.1016/0378-1119(83)90230-5. View

18.

Queen C, Korn L . A comprehensive sequence analysis program for the IBM personal computer. Nucleic Acids Res. 1984; 12(1 Pt 2):581-99. PMC: 321072. DOI: 10.1093/nar/12.1part2.581. View

19.

Church G, Gilbert W . Genomic sequencing. Proc Natl Acad Sci U S A. 1984; 81(7):1991-5. PMC: 345422. DOI: 10.1073/pnas.81.7.1991. View

20.

Szabo P, Grzeschik K, SINISCALCO M . A human autosomal phosphoglycerate kinase locus maps near the HLA cluster. Proc Natl Acad Sci U S A. 1984; 81(10):3167-9. PMC: 345242. DOI: 10.1073/pnas.81.10.3167. View