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Use of Clozapine Alongside Chemotherapy in a Treatment-resistant Bipolar Disorder Patient with Ovarian Carcinoma: A Case Report and Brief Review

Overview
Specialty Psychiatry
Date 2017 Feb 16
PMID 28197007
Citations 2
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Abstract

Regular monitoring of blood counts ensures the safety of clozapine use; however, certain clinical situations may pose a dilemma for management such as use of clozapine in the presence of myelosuppressive chemotherapy. Further, there is very limited literature to guide such decisions. We report a case of a clozapine-stabilized, treatment-resistant bipolar disorder patient with ovarian carcinoma requiring chemotherapy. The clinical challenges are discussed in light of a brief review of the available reports.

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