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Overview

Journal Evid Based Preclin Med

Publisher Wiley

Date 2017 Feb 7

PMID 28163925

Authors

Malcolm Macleod

Affiliations

Soon will be listed here.

References

Bailey K . Detecting fabrication of data in a multicenter collaborative animal study. Control Clin Trials. 1991; 12(6):741-52. DOI: 10.1016/0197-2456(91)90037-m. View

van der Worp H, Sena E, Donnan G, Howells D, Macleod M . Hypothermia in animal models of acute ischaemic stroke: a systematic review and meta-analysis. Brain. 2007; 130(Pt 12):3063-74. DOI: 10.1093/brain/awm083. View

Antonic A, Sena E, Lees J, Wills T, Skeers P, Batchelor P . Stem cell transplantation in traumatic spinal cord injury: a systematic review and meta-analysis of animal studies. PLoS Biol. 2013; 11(12):e1001738. PMC: 3866091. DOI: 10.1371/journal.pbio.1001738. View

Jansen of Lorkeers S, Eding J, Vesterinen H, van der Spoel T, Sena E, Duckers H . Similar effect of autologous and allogeneic cell therapy for ischemic heart disease: systematic review and meta-analysis of large animal studies. Circ Res. 2014; 116(1):80-6. DOI: 10.1161/CIRCRESAHA.116.304872. View

OCollins V, Macleod M, Donnan G, Horky L, van der Worp B, Howells D . 1,026 experimental treatments in acute stroke. Ann Neurol. 2006; 59(3):467-77. DOI: 10.1002/ana.20741. View

Hackam D . Translating animal research into clinical benefit. BMJ. 2007; 334(7586):163-4. PMC: 1782020. DOI: 10.1136/bmj.39104.362951.80. View

Rooke E, Vesterinen H, Sena E, Egan K, Macleod M . Dopamine agonists in animal models of Parkinson's disease: a systematic review and meta-analysis. Parkinsonism Relat Disord. 2011; 17(5):313-20. DOI: 10.1016/j.parkreldis.2011.02.010. View

Sena E, van der Worp H, Howells D, Macleod M . How can we improve the pre-clinical development of drugs for stroke?. Trends Neurosci. 2007; 30(9):433-9. DOI: 10.1016/j.tins.2007.06.009. View

Ioannidis J, Greenland S, Hlatky M, Khoury M, Macleod M, Moher D . Increasing value and reducing waste in research design, conduct, and analysis. Lancet. 2014; 383(9912):166-75. PMC: 4697939. DOI: 10.1016/S0140-6736(13)62227-8. View

10.

Ter Riet G, Korevaar D, Leenaars M, Sterk P, van Noorden C, Bouter L . Publication bias in laboratory animal research: a survey on magnitude, drivers, consequences and potential solutions. PLoS One. 2012; 7(9):e43404. PMC: 3434185. DOI: 10.1371/journal.pone.0043404. View

11.

Sena E, Briscoe C, Howells D, Donnan G, Sandercock P, Macleod M . Factors affecting the apparent efficacy and safety of tissue plasminogen activator in thrombotic occlusion models of stroke: systematic review and meta-analysis. J Cereb Blood Flow Metab. 2010; 30(12):1905-13. PMC: 3002882. DOI: 10.1038/jcbfm.2010.116. View

12.

Vesterinen H, Sena E, ffrench-Constant C, Williams A, Chandran S, Macleod M . Improving the translational hit of experimental treatments in multiple sclerosis. Mult Scler. 2010; 16(9):1044-55. DOI: 10.1177/1352458510379612. View

13.

Hirst T, Vesterinen H, Sena E, Egan K, MacLeod M, Whittle I . Systematic review and meta-analysis of temozolomide in animal models of glioma: was clinical efficacy predicted?. Br J Cancer. 2013; 108(1):64-71. PMC: 3553514. DOI: 10.1038/bjc.2012.504. View

14.

Tsilidis K, Panagiotou O, Sena E, Aretouli E, Evangelou E, Howells D . Evaluation of excess significance bias in animal studies of neurological diseases. PLoS Biol. 2013; 11(7):e1001609. PMC: 3712913. DOI: 10.1371/journal.pbio.1001609. View

15.

Bebarta V, Luyten D, Heard K . Emergency medicine animal research: does use of randomization and blinding affect the results?. Acad Emerg Med. 2003; 10(6):684-7. DOI: 10.1111/j.1553-2712.2003.tb00056.x. View

16.

Sena E, van der Worp H, Bath P, Howells D, Macleod M . Publication bias in reports of animal stroke studies leads to major overstatement of efficacy. PLoS Biol. 2010; 8(3):e1000344. PMC: 2846857. DOI: 10.1371/journal.pbio.1000344. View

17.

Fang F, Steen R, Casadevall A . Misconduct accounts for the majority of retracted scientific publications. Proc Natl Acad Sci U S A. 2012; 109(42):17028-33. PMC: 3479492. DOI: 10.1073/pnas.1212247109. View