Malcolm Macleod
Overview
Explore the profile of Malcolm Macleod including associated specialties, affiliations and a list of published articles.
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91
Citations
6897
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Recent Articles
1.
Smith K, Boyce N, Chevance A, Chiocchia V, Correll C, Donoghue K, et al.
Br J Psychiatry
. 2024 Dec;
:1-9.
PMID: 39710623
Background: Trace amine-associated receptor 1 (TAAR1) agonists offer a new approach, but there is uncertainty regarding their effects, exact mechanism of action and potential role in treating psychosis. Aims: To...
2.
Wilson E, Currie G, Macleod M, Kind P, Sena E
Brain Neurosci Adv
. 2024 Oct;
8:23982128241287279.
PMID: 39431203
Using genetically modified animals to model neurodevelopmental conditions helps better our understanding of biology underlying these conditions. Animal research has unique characteristics not shared with clinical research, meaning systematic review...
3.
Ostinelli E, Chiocchia V, Macleod M, Browning M, Harmer C, Siafis S, et al.
Wellcome Open Res
. 2024 Jul;
8:425.
PMID: 39026608
Anhedonia is a key symptom of depression, and it has been suggested as a potential target for future individualised treatments. However, much is unknown about how interventions enhancing dopaminergic pathways...
4.
Vacek A, Mair G, White P, Bath P, Muir K, Salman R, et al.
J Stroke Cerebrovasc Dis
. 2023 Nov;
33(1):107512.
PMID: 38007987
Background: The extent and distribution of intracranial hemorrhage (ICH) directly affects clinical management. Artificial intelligence (AI) software can detect and may delineate ICH extent on brain CT. We evaluated e-ASPECTS...
5.
Hair K, Bahor Z, Macleod M, Liao J, Sena E
BMC Biol
. 2023 Sep;
21(1):189.
PMID: 37674179
Background: Researchers performing high-quality systematic reviews search across multiple databases to identify relevant evidence. However, the same publication is often retrieved from several databases. Identifying and removing such duplicates ("deduplication")...
6.
Butler J, Jacobs N, Macleod M, Munafo M
J Neurosci Methods
. 2023 Aug;
397:109949.
PMID: 37586662
There is growing awareness that the ways in which academic research is conducted could be improved. A number of exciting innovations are emerging, alongside a broader agenda that includes a...
7.
Cipriani A, Seedat S, Milligan L, Salanti G, Macleod M, Hastings J, et al.
BMJ Ment Health
. 2023 Jun;
26(1).
PMID: 37290906
In anxiety, depression and psychosis, there has been frustratingly slow progress in developing novel therapies that make a substantial difference in practice, as well as in predicting which treatments will...
8.
Hair K, Wilson E, Wong C, Tsang A, Macleod M, Bannach-Brown A
Clin Sci (Lond)
. 2023 May;
137(10):773-784.
PMID: 37219941
Systematic reviews and meta-analysis are the cornerstones of evidence-based decision making and priority setting. However, traditional systematic reviews are time and labour intensive, limiting their feasibility to comprehensively evaluate the...
9.
Mair G, White P, Bath P, Muir K, Martin C, Dye D, et al.
Ann Clin Transl Neurol
. 2023 May;
10(7):1072-1082.
PMID: 37208850
Objective: Software developed using artificial intelligence may automatically identify arterial occlusion and provide collateral vessel scoring on CT angiography (CTA) performed acutely for ischemic stroke. We aimed to assess the...
10.
Wong C, Gregory J, Liao J, Egan K, Vesterinen H, Ahmad Khan A, et al.
BMJ Open
. 2023 Feb;
13(2):e064169.
PMID: 36725099
Objectives: Motor neuron disease (MND) is an incurable progressive neurodegenerative disease with limited treatment options. There is a pressing need for innovation in identifying therapies to take to clinical trial....