A Versatile Platform for Surface Modification of Microfluidic Droplets

Overview

Journal Lab Chip

Publisher Royal Society of Chemistry

Specialties Biotechnology
Chemistry

Date 2017 Feb 4

PMID 28154857

Citations 4

Authors

Mingqiang Li

Weiqian Jiang

Zaozao Chen

Smruthi Suryaprakash

Shixian Lv

Zhaohui Tang

Xuesi Chen

Kam W Leong

Affiliations

Soon will be listed here.

Abstract

To advance emulsion droplet technology, we synthesize functional derivatives of Pluronic F127 that can simultaneously act as surfactants and as reactive sites for droplet surface decoration. The amine-, carboxyl-, N-hydroxysuccinimide ester-, maleimide- and biotin-terminated Pluronic F127 allows ligand immobilization on single-emulsion or double-emulsion droplets via electrostatic adsorption, covalent conjugation or site-specific avidin-biotin interaction.

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