Interfacial Nano-biosensing in Microfluidic Droplets for High-sensitivity Detection of Low-solubility Molecules

Overview

Journal Chem Commun (Camb)

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2016 Jan 14

PMID 26759838

Citations 20

Authors

Maowei Dou

Jose Mireles Garcia Jr

Sihui Zhan

XiuJun Li

Affiliations

Soon will be listed here.

Abstract

Taking advantage of the properties of the high surface-area-to-volume ratio of microfluidic droplets, we developed an innovative interfacial nanosensing strategy based on aptamer-functionalized graphene oxide nanosensors in microfluidic droplets for the high-sensitivity one-step detection of 17β-estradiol and other low-solubility molecules, with the detection sensitivity improved by about 3 orders of magnitude compared to conventional systems.

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