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NNKTT120, an Anti-iNKT Cell Monoclonal Antibody, Produces Rapid and Sustained INKT Cell Depletion in Adults with Sickle Cell Disease

Overview
Journal PLoS One
Date 2017 Feb 3
PMID 28152086
Citations 21
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Abstract

Trial Registration: clinicaltrials.gov NCT01783691.

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References
1.
Field J, Lin G, Okam M, Majerus E, Keefer J, Onyekwere O . Sickle cell vaso-occlusion causes activation of iNKT cells that is decreased by the adenosine A2A receptor agonist regadenoson. Blood. 2013; 121(17):3329-34. PMC: 3637009. DOI: 10.1182/blood-2012-11-465963. View

2.
Cox D, Fox L, Tian R, Bardet W, Skaley M, Mojsilovic D . Determination of cellular lipids bound to human CD1d molecules. PLoS One. 2009; 4(5):e5325. PMC: 2673035. DOI: 10.1371/journal.pone.0005325. View

3.
Scheuplein F, Lamont D, Poynter M, Boyson J, Serreze D, Lundblad L . Mouse Invariant Monoclonal Antibody NKT14: A Novel Tool to Manipulate iNKT Cell Function In Vivo. PLoS One. 2015; 10(10):e0140729. PMC: 4608835. DOI: 10.1371/journal.pone.0140729. View

4.
De Santo C, Salio M, Masri S, Lee L, Dong T, Speak A . Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans. J Clin Invest. 2008; 118(12):4036-48. PMC: 2582442. DOI: 10.1172/JCI36264. View

5.
Gapin L, Matsuda J, Surh C, Kronenberg M . NKT cells derive from double-positive thymocytes that are positively selected by CD1d. Nat Immunol. 2001; 2(10):971-8. DOI: 10.1038/ni710. View