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UniProt Protein Knowledgebase

Overview
Journal Methods Mol Biol
Specialty Molecular Biology
Date 2017 Feb 3
PMID 28150232
Citations 115
Authors
Sangya Pundir
Maria J Martin
Claire ODonovan
Affiliations
Soon will be listed here.
Abstract

The Universal Protein Resource (UniProt) is a freely available comprehensive resource for protein sequence and annotation data. UniProt is a collaboration between the European Bioinformatics Institute (EMBL-EBI), the Swiss Institute of Bioinformatics (SIB), and the Protein Information Resource (PIR). Across the three institutes more than 100 people are involved through different tasks such as expert curation, software development, and support.This chapter introduces the functionality and data provided by UniProt. It describes example use cases for which you might come to UniProt and the methods to help you achieve your goals.

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References
1.
Sievers F, Wilm A, Dineen D, Gibson T, Karplus K, Li W . Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega. Mol Syst Biol. 2011; 7:539. PMC: 3261699. DOI: 10.1038/msb.2011.75. View
2.
Ladunga I . Finding Homologs in Amino Acid Sequences Using Network BLAST Searches. Curr Protoc Bioinformatics. 2017; 59:3.4.1-3.4.24. DOI: 10.1002/cpbi.34. View
3.
Magrane M . UniProt Knowledgebase: a hub of integrated protein data. Database (Oxford). 2011; 2011:bar009. PMC: 3070428. DOI: 10.1093/database/bar009. View
4.
. UniProt: a hub for protein information. Nucleic Acids Res. 2014; 43(Database issue):D204-12. PMC: 4384041. DOI: 10.1093/nar/gku989. View
5.
Huang H, McGarvey P, Suzek B, Mazumder R, Zhang J, Chen Y . A comprehensive protein-centric ID mapping service for molecular data integration. Bioinformatics. 2011; 27(8):1190-1. PMC: 3072559. DOI: 10.1093/bioinformatics/btr101. View