Ancylostoma Ceylanicum Hookworm in the Solomon Islands

Overview

Journal Emerg Infect Dis

Specialty Infectious Diseases

Date 2017 Jan 19

PMID 28098526

Citations 28

Authors

Richard S Bradbury

Sze Fui Hii

Humpress Harrington

Richard Speare

Rebecca Traub

Affiliations

Soon will be listed here.

Abstract

Although hookworm is highly prevalent in the Solomon Islands, the species involved are unknown. We initiated this study in response to finding Ancylostoma ceylanicum hookworm in a peacekeeper in Australia who had returned from the Solomon Islands. Kato-Katz fecal surveys performed in 2013 and 2014 in 2 village groups in East Malaita, Solomon Islands, identified hookworm-positive samples. These specimens were tested by cytochrome oxidase 1 (cox-1) gene multiplex PCR and sequenced. Of 66 positive specimens, 54 (81.8%) contained only Necator americanus, 11 (16.7%) contained only A. ceylanicum, and 1 (1.5%) contained both species. A. duodenale was not found. Haplotype analysis of cox-1 sequences placed all human isolates (99% bootstrap support) of A. ceylanicum within the zoonotic clade rather than the human-specific clade. This study confirms that A. ceylanicum is endemic in the East Malaita region of this Pacific Island nation. The strain of the A. ceylanicum in this region can be shared among humans, dogs, and cats.

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References

Koehler A, Bradbury R, Stevens M, Haydon S, Jex A, Gasser R . Genetic characterization of selected parasites from people with histories of gastrointestinal disorders using a mutation scanning-coupled approach. Electrophoresis. 2013; 34(12):1720-8. DOI: 10.1002/elps.201300100. View

Kayser M, Brauer S, Cordaux R, Casto A, Lao O, Zhivotovsky L . Melanesian and Asian origins of Polynesians: mtDNA and Y chromosome gradients across the Pacific. Mol Biol Evol. 2006; 23(11):2234-44. DOI: 10.1093/molbev/msl093. View

Carroll S, Grove D . Experimental infection of humans with Ancylostoma ceylanicum: clinical, parasitological, haematological and immunological findings. Trop Geogr Med. 1986; 38(1):38-45. View

Yoshida Y . Comparative studies on Ancylostoma braziliense and Ancylostoma ceylanicum. II. The infective larval stage. J Parasitol. 1971; 57(5):990-2. View

Hotez P, Whitham M . Helminth infections: a new global women's health agenda. Obstet Gynecol. 2014; 123(1):155-160. DOI: 10.1097/AOG.0000000000000025. View

Traub R . Ancylostoma ceylanicum, a re-emerging but neglected parasitic zoonosis. Int J Parasitol. 2013; 43(12-13):1009-15. DOI: 10.1016/j.ijpara.2013.07.006. View

Harrington H, Bradbury R, Taeka J, Asugeni J, Asugeni V, Igeni T . Prevalence of soil-transmitted helminths in remote villages in East Kwaio, Solomon Islands. Western Pac Surveill Response J. 2015; 6(3):51-8. PMC: 4675160. DOI: 10.5365/WPSAR.2015.6.1.016. View

Smith J, Brooker S . Impact of hookworm infection and deworming on anaemia in non-pregnant populations: a systematic review. Trop Med Int Health. 2010; 15(7):776-95. PMC: 2916221. DOI: 10.1111/j.1365-3156.2010.02542.x. View

Pullan R, Smith J, Jasrasaria R, Brooker S . Global numbers of infection and disease burden of soil transmitted helminth infections in 2010. Parasit Vectors. 2014; 7:37. PMC: 3905661. DOI: 10.1186/1756-3305-7-37. View

10.

Inpankaew T, Schar F, Dalsgaard A, Khieu V, Chimnoi W, Chhoun C . High prevalence of Ancylostoma ceylanicum hookworm infections in humans, Cambodia, 2012. Emerg Infect Dis. 2014; 20(6):976-82. PMC: 4036766. DOI: 10.3201/eid2006.131770. View

11.

ANTEN J, ZUIDEMA P . Hookworm infection in Dutch servicemen returning from West New Guinea. Trop Geogr Med. 1964; 16:216-24. View

12.

Walker A, BELLMAINE S . Severe alimentary bleeding associated with hookworm infestation in aboriginal infants. Med J Aust. 1975; 1(24):751-2. View

13.

Katz N, Chaves A, Pellegrino J . A simple device for quantitative stool thick-smear technique in Schistosomiasis mansoni. Rev Inst Med Trop Sao Paulo. 1972; 14(6):397-400. View

14.

Ng-Nguyen D, Hii S, Nguyen V, Nguyen T, Van Nguyen D, Traub R . Re-evaluation of the species of hookworms infecting dogs in Central Vietnam. Parasit Vectors. 2015; 8:401. PMC: 4517506. DOI: 10.1186/s13071-015-1015-y. View

15.

Traub R, Inpankaew T, Sutthikornchai C, Sukthana Y, Thompson R . PCR-based coprodiagnostic tools reveal dogs as reservoirs of zoonotic ancylostomiasis caused by Ancylostoma ceylanicum in temple communities in Bangkok. Vet Parasitol. 2008; 155(1-2):67-73. DOI: 10.1016/j.vetpar.2008.05.001. View

16.

Traub R, Hobbs R, Adams P, Behnke J, Harris P, Thompson R . A case of mistaken identity--reappraisal of the species of canid and felid hookworms (Ancylostoma) present in Australia and India. Parasitology. 2006; 134(Pt 1):113-9. DOI: 10.1017/S0031182006001211. View

17.

Hughes R, Sharp D, Hughes M, Akauola S, Heinsbroek P, Velayudhan R . Environmental influences on helminthiasis and nutritional status among Pacific schoolchildren. Int J Environ Health Res. 2004; 14(3):163-77. DOI: 10.1080/0960312042000218589. View

18.

Feary J, Venn A, Mortimer K, Brown A, Hooi D, Falcone F . Experimental hookworm infection: a randomized placebo-controlled trial in asthma. Clin Exp Allergy. 2009; 40(2):299-306. PMC: 2814083. DOI: 10.1111/j.1365-2222.2009.03433.x. View

19.

Speare R, Bradbury R, Croese J . A Case of Ancylostoma ceylanicum Infection Occurring in an Australian Soldier Returned from Solomon Islands. Korean J Parasitol. 2016; 54(4):533-6. PMC: 5040074. DOI: 10.3347/kjp.2016.54.4.533. View

20.

Ngui R, Mahdy M, Chua K, Traub R, Lim Y . Genetic characterization of the partial mitochondrial cytochrome oxidase c subunit I (cox 1) gene of the zoonotic parasitic nematode, Ancylostoma ceylanicum from humans, dogs and cats. Acta Trop. 2013; 128(1):154-7. DOI: 10.1016/j.actatropica.2013.06.003. View