High Prevalence of Ancylostoma Ceylanicum Hookworm Infections in Humans, Cambodia, 2012

Overview

Journal Emerg Infect Dis

Specialty Infectious Diseases

Date 2014 May 29

PMID 24865815

Citations 80

Authors

Tawin Inpankaew

Fabian Schar

Anders Dalsgaard

Virak Khieu

Wissanuwat Chimnoi

Chamnan Chhoun

Daream Sok

Hanspeter Marti

Sinuon Muth

Peter Odermatt

Rebecca J Traub

Affiliations

Soon will be listed here.

Abstract

Ancylostoma ceylanicum, a hookworm of canids and felids in Asia, is becoming the second most common hookworm infecting humans. In 2012, we investigated the prevalence and infection dynamics of and risk factors for hookworm infections in humans and dogs in a rural Cambodian village. Over 57% of the population was infected with hookworms; of those, 52% harbored A. ceylanicum hookworms. The greatest intensities of A. ceylanicum eggs were in persons 21-30 years of age. Over 90% of dogs also harbored A. ceylanicum hookworms. Characterization of the cytochrome oxidase-1 gene divided isolates of A. ceylanicum hookworms into 2 groups, 1 containing isolates from humans only and the other a mix of isolates from humans and animals. We hypothesize that preventative chemotherapy in the absence of concurrent hygiene and animal health programs may be a factor leading to emergence of A. ceylanicum infections; thus, we advocate for a One Health approach to control this zoonosis.

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