Kidney Volume and Ambulatory Blood Pressure in Children

Overview

Journal J Clin Hypertens (Greenwich)

Specialty Cardiology & Vascular Diseases

Date 2016 Dec 17

PMID 27982509

Citations 4

Authors

Shari Gurusinghe

Arkadiy Palvanov

Mark E Bittman

Pamela Singer

Rachel Frank

Nataliya Chorny

Lulette Infante

Christine B Sethna

Affiliations

Soon will be listed here.

Abstract

Low nephron number has been shown to be a risk factor for hypertension (HTN) in adulthood. Kidney volume may serve as a surrogate marker for nephron mass. The relationship between kidney volume and ambulatory blood pressure (BP) in the pediatric population is not known. A retrospective chart review of children younger than 21 years who were evaluated for HTN was performed. Twenty-four-hour BP and ultrasonography data were obtained. Multiple regression was used to examine associations between BP and kidney volume. Of 84 children (mean age 13.87 years, 72.6% males), 54 had HTN. Systolic BP index during the awake, sleep, and 24-hour periods (all P≤.05) was found to be positively correlated with total kidney volume. Greater total kidney volume was found to be a positive predictor of 24-hour and sleep systolic index (P≤.05). It failed to serve as a predictor of HTN, pre-HTN, or white-coat HTN. Contrary to expectation, total kidney volume was positively associated with systolic BP indices.

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Kidney volume and ambulatory blood pressure in children.

Gurusinghe S, Palvanov A, Bittman M, Singer P, Frank R, Chorny N J Clin Hypertens (Greenwich). 2016; 19(5):498-503.

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